Clinical and bacteriological aspects of acinetobacter septicemia

Two hundred and seven patients attended Aim Shams Univesity hospital and suspected to have septicemia were included in the study. Blood cultures were performed to all patients. Forty-two [20%] blood cultures were positive, of which 6 isolates [2.9%] were Acinetobacter species. Acinetobacter thus represents 6 of 42 [14.3%] of all bacteremias. Four of the six isolates were A. baumannii [66.7%] and two cases were A. lwoffii [33.3%]. The isolated Acinetobacter strains were resistant to most of antimicrobial agents. Five strains were sensitive to ampicillin/sulbactam and imipenema. Three strains were sensitive to ciprofloxacin and amikacin and only one was sensitive to tobramycin. We recommended the use of ampicillin/sulbactam or imipenem in treatment of Acinetobacter septicemia however, susceptibility testing should be done to select the best antimicrobial drug for therapy

Ureaplasma urealyticum as a causative organism of urinary tract infection stones

Ureaplasma urealyticum is a fastidious organism which is not recovered by conventional bacterial cultures techniques, but special cultures are required for its isolation and identification. As it is a urease-producing organism, it is considered a risk factor for the formation of struvite calculi in the urinary tract. A total of 30 patients with urinary infection stones [19 of them with the 1[st] stone formation and 11 with recurrent stone formation] were included in the study. Both bladder urine specimen [cystoscopically obtained] and stones removed were subjected to conventional cultures and also to Ureaplasma specific cultures [A7 agar and U9 broth]. The results of culture techniques revealed that 86.7% of patients had aerobic organisms [E. coli in 46.7%, Klebsiella in 30%, Proteus in 6.7% and Pseudomonas in 3.3% and 26.7% showed U. urealyticum in mid stream urine As regards stone cultures, they revealed aerobic organisms in 76.7%, and U. urealyticum in 20%. sensitivity tests for U. urealyticum showed that minocycline was the most effective antimicrobial followed by tetracycline and ciprofloxacin From these data, we conclude that U. urealyticum may be the causative organism for infection stone and should be searched for via its specific cultures, especially in patients with recurrent stones and with the so-called sterile pyuria