RESUMO
Background: Diabetes mellitus, in particular, has emerged as a significant health concern, affecting millions of individuals and placing a considerable strain on the healthcare system. Promoting remission of diabetes, wherein patients achieve a state of sustained blood sugar control without the need for ongoing medication or with a reduced reliance on medication, can yield remarkable benefits. This study sought to understand the role of Aahar and Panchakarma on restoration of euglycemia in known type 2 diabetes patients. Methods: A retrospective, observational, cohort study was conducted at Madhavbaug Cardiac Care Clinic between April 2021 and April 2022 in Maharashtra, India. Patients aged 18 years and older with a diagnosis of type 2 diabetes mellitus with glycated haemoglobin level (HbA1c) >7% and had participated in the Comprehensive Diabetes Care (CDC) program were included in this study. Parameters such as HbA1c, body weight, body mass index (BMI), and dependence on conventional allopathic medication were assessed at the end of the CDC program. Follow-up was conducted at 90 days. Day 1 and day 90 data were compared. Results: Of the 45 patients, 17 (40.5%) patients had a negative glucose tolerance and 14 (33.3%) patients had impaired glucose tolerance. HbA1c, body weight, and BMI improved at the end of CDC program. Dependency on conventional allopathic medications was also reduced. Conclusions: Restoration of euglycemia in patients with type 2 diabetes mellitus is possible, however, further studies to understand the affecting factors are warranted.
RESUMO
Background: Colposcopic evaluation and guided biopsy is an important diagnostic step and standard of management for abnormal cytology smears in developed countries. Aim: The present study evaluates the performance of colposcopy vs conventional cytology in estimating the presence and grade of cervical disease against the reference standard of histopathology as a secondary test modality to triage women found positive on primary screening by visual inspection with 5% acetic acid (VIA). Settings and Design: Colposcopy and directed biopsy were performed after primary screening for cervical cancer in an urban hospital cancer screening clinic between January 2000 and June 2005, in Mumbai, India. Materials and Methods: Healthy women (8863) in the age group of 35-65 years participated in the cervical cancer early detection program in the hospital and community cancer screening clinics in Mumbai. Women found positive on the primary screening test by VIA underwent diagnostic evaluation by Pap smear cytology and colposcopy evaluation with directed biopsies. Statistical Analysis: Accuracy parameters and their 95% confidence intervals were calculated using 2 Χ 2 tables and standard formulae. Results: The test range of sensitivity of colposcopy for the detection of histologically confirmed cervical intraepithelial neoplasia grade 1+ (CIN1+) or CIN2+ was 58.0-74.7% and that of specificity was 57.5-92.9%. The sensitivity and specificity of cytology to detect CIN2+ was 57.4% and 99.4%, respectively. Conclusion: Colposcopy is a good sensitive test for the detection of CIN and can be considered as a secondary testing tool to triage women found positive on VIA.