RESUMO
Tc-99m-pertechnetate and I-131 radionuclides have been utilized widely in diagnosis and therapy for different thyroid diseases. Radionuclide administration is absolutely contraindication in pregnant women, particularly during early pregnancy to avoid interval the effects of ionizing radiation emitted from administrated radionuclides for both fetus, and the pregnant mother. This study depended on a recorded survey for pregnant women who had received oversightly either Tc-99m-pertechnetate intravenously or I-131 orally. Only fifty-seven pregnant women with different thyroid disorders were received oversightly intravenous Tc-99m pertechnetate doses to perform thyroid scintigraphy or orally I-131 doses for therapy purposes either in first or second trimester of pregnancy. Of those patients, 30 pregnant patients had received 2mCi [74MBq] dose of Tc-99m pertechnetate for thyroid scintigraphic studies, and 27 pregnant patients had received 10 to 25mCi [370 to 925MBq] I-131 therapy doses for treatment of hyperthyroidism and 10 to 25mCi [370 to 925MBq] for treatment of well-differentiated thyroid carcinomas 50 to 150mCi [1.8 to 5.5GBq]. It is fruitful to report one case with thyroid cancer that had treated inadvertently by I-131 therapy dose [50 mCi] during pregnancy as an example case to confirm our report, but she delivered a healthy daughter and no evidence of any congenital anomalies. Thus the daughter of this women was still under our followed up to date [18 year old], and we do not find any thyroid or other obvious body organs abnormalities. This study demonstrated that there was no evidence of any newborn anomalies or thyroid dysfunction presented during our follow up of those patients. We recommended that further animal studies for such issue to evaluate the effect of ionizing radiation due to I-131, which are frequently used in therapeutic purposes in medicine. Thus, we emphasize on many Obligatory advises that should be applied, clinically, inorder to prevent the occurrence of oversight administration of radionuclides. But, for the time being, we recommend that either ten days principle or 48 hour pregnancy test method should be done as a mandatory test before administration of any radionuclide to childbearing women to avoid any complications and to assure our patients