Primary Intraosseous Squamous Cell Carcinoma Arising from Parakeratinized Kerato - Cystic Odontogenic Tumor Associated with Impacted Mandibular Canine: A Rare Entity.

Primary intraosseous carcinoma (PIOC) that arises from the epithelial lining of odontogenic cyst is a rare entity that represents about 1-2% of all oral and maxillofacial carcinoma. In particular, PIOC arising from keratocystic odontogenic tumor (KCOT) is rare when compared with such occurrence in other odontogenic cysts such as radicular cyst, residual cyst, and dentigerous cyst. Th e following case report discusses a case of squamous cell carcinoma arising from parakeratinized KCOT associated with impacted mandibular canine in a 43-year-old male patient with a complaint of painful swelling in the mandible. A review of reported cases from 1981 of PIOC arising from KCOT alone is also included.