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Background:The ongoing mutation of the COVID-19 virus causes an increase in transmission and a decrease in vaccine effectiveness. COVID-19 cases since the end of 2021 have continued to increase, and data on the characteristics of patients with confirmed COVID-19 at Sanglah hospital for this period is not yet available. Therefore, this study aims to determine the characteristics of confirmed COVID-19 patients who received treatment at Sanglah hospital from January to February 2022.Methods:This study is a descriptivestudy using a cross-sectional approach taken from medical record data.Results:There were 276 COVID-19 patient subjects with an average age of 53 years, consisting of 51.1% male and 48.9% female. Most occupations are private employees, 29.0%. The 39.5% of patients had mild symptoms, and 5.8% had critical symptoms. Cough (51.8%) and fever (40.6%) were the main clinical symptoms, and chronic kidney disease was the most common comorbidity at 16.7%. As many as 46.0% of COVID-19 patients have received vaccines at least 2x, and 2.9% of patients are previous COVID-19 survivors.Conclusions:The characteristics of confirmed COVID-19 patients who received treatment at Sanglah hospital in January and February 2022 were more male than female, with the most jobs as private employees. Most patients have mild to moderate symptoms with a chief complaint of cough. Almost half of the patients have been vaccinated at least 2x. Most of them are not COVID-19 survivors.
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Background:Omicron (B.1.1.529) is a variant of COVID-19 which is first reported from Gauteng Province, South Africa in November 2021. This variant was considered the fifth variant of concern (VOC) by the world health organization (WHO) due to its much faster transmission but with milder clinical manifestations than other COVID-19 variants.Methods:This retrospective cross-sectional descriptive study was conducted in Sanglah general hospital, Denpasar, Bali in March 2022. Subjects of this study were all patients who were diagnosed with probable COVID-19 Omicron by having a positive S-gene target failure (SGTF) of a reverse transcriptase polymerase chain reaction (RT-PCR) test in Sanglah general hospital from January to February 2022. All subjects must age 18 years oldor older. Data on patient characteristics and clinical manifestations were obtained from medical record data and analyzed using statistical package for service solution (SPSS) for windows version 25.Results:A total of 79 probable COVID-19 Omicron patients were analyzed in this study. Most of them were elderly who age more than 65 years old (30.4%), male (50.6%), and work as an entrepreneur (24.1%). The majority of probable COVID-19 Omicron patients were symptomatic (89.9%) with the most common clinical manifestation found was cough (54.9%). Other clinical manifestations found were shortness of breath (50.7%), fever (38.0%), fatigue (21.1%), runny nose (11.3%), sore throat (8.5%), nausea and vomit (2.8%), headache (1.4%), diarrhea (1.4%), and anosmia (1.4%).Conclusions:The clinical manifestations of probable COVID-19 Omicron patients vary but most of them were classified as mild symptoms
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Background:Lung cancer is ranked third as the most common cancer in Indonesia. The one-year survival rate of advanced-stage non-smallcell lung carcinoma (NSCLC) patient is quite low, that is 24.6%. Effective and inexpensive prognostic markers need to be further studied due to an increasing incidence of cancer. Inflammation plays an important role in tumorigenesis and research showed an association of NLR and PLR values with poor prognosis in patients with various solid tumors, but current cutoff values still vary. This study wanted to determine the value of NLR, PLR and their relationship with the survival rate of advancedstage NSCLC patients at Sanglah hospital.Methods:A retrospective cohort study using the medical record of 96 advanced-stage NSCLC patients who underwent treatment since January 2018 in Sanglah hospital, was closely monitored for a year since diagnosed. Analysis was performed with ROC, Kaplan Meier analysis, log rank test, and time independent cox regression model.Results:The one-yearsurvival rate of advancedstage NSCLC patient is 14.6%, with median survival 3.26 months. Cut off NLR> 3.37, median survival 2.66,p=0.00. Cut off PLR>178.55, median survival 3.26, p=0.35. Multivariate analysis showed that NLR, HR=2.75 and performance status, HR=1.78 were associated with survival.Conclusions:NLR with cut off>3.37 is associated with one-year survival rate of advanced-stage NSCLC patient. PLR did not have any significant association with one-year survival rate of advanced-stage NSCLC patient.