RESUMO
AIM: To find out the effect of heparin on the incidence of posterior capsular opacification after cataract surgery in children
STUDY DESIGN: Quasi Experimental Design
PLACE AND DURATION OF STUDY: REDO Eye Hospital, Rawalpindi from Jan 2008 to Jan 2011
MATERIALS AND METHODS: Twenty eyes of fifteen patients aging 4 to 10 years with uncomplicated pediatric cataracts were selected in the study. The children were operated for cataract under general anesthesia and the anterior chamber was irrigated with heparin sodium [5 IU/cc] while added to balanced salt solution [BSS Plus]. All patients received standardized postoperative treatment. All patients were followed on the first post operative day, after one week, after one month and were advised follow up at the 3rd, 6th months and one year postoperatively for the incidence of PCO
RESULTS: No fibrinous reaction or membrane or synechias formation on the pupil was observed. Posterior capsular opacification [PCO] was observed in 10 % cases after 6 months and in 15% cases after one year
CONCLUSION: After irrigating the anterior chamber with Heparin sodium in cataract surgery of children the incidence of PCOwas 15% on one year follow up
RESUMO
To find out the effects of heparin added to the irrigating solution on anterior chamber reaction in pediatric cataract surgery. A quasi experimental study. This study was conducted in a tertiary eye care hospital from Jan 2008 to July 2010. Twenty eyes of fifteen patients aging 4 years to 10 years with uncomplicated pediatric cataract were selected in the study. All children underwent cataract extraction under general anesthesia and received anterior chamber irrigation with heparin sodium [5 ILJ/cc] during operation added to the irrigating solution of balanced salt solution [BSS Plus]. All patients received standardized postoperative treatment. All patients were followed on the first post operative day, after one week, after one month and were advised follow up at the 3[rd] and 6th months and postoperative anterior chamber reaction was documented according to modified Hogan's classification on each visit. Mild anterior chamber reaction was observed in 10 patients [50%] and moderate anterior reaction was observed in only [15%] three patients on first follow up. Anterior chamber reaction disappeared on 7[th] post operative day in all patients. Fibrin formation, anterior and posterior synechia, cyclitic and pupillary membrane formation was not observed in any patient. There was also no intraocular lens deposits or posterior capsular opacification [PCO] in any of the cases afterthe follow up of 6[th] months. Heparin sodium in the irrigating solution is safe, effective, and promising method to prevent early postoperative inflammatory reaction in pediatric cataract surgery