RESUMO
Neurofibromatosis type 1 [NF-1] is an autosomal dominantly inherited disease characterized by cafe-au-lait spots, neurofibromas, axillary freckling, Lisch nodules of iris, gliomas and various systemic vascular ischemic manifestations mainly in the aorta, brain and kidney. Retinal vascular manifestations in patients with NF-1 are usually representative of retinal capillary hemangiomatosis. Few cases of NF-1 with retinal vascular occlusive disease have been described. We describe a young Indian woman with NF-1 with unilateral peripheral retinal ischemia but no vascular abnormality at the posterior pole
Assuntos
Humanos , Feminino , Adulto , Isquemia , Retina , Vasos Retinianos , Neurofibromatose 1 , Manchas Café com LeiteRESUMO
Congenital retinal macrovessel [CRM] refers to an aberrant vessel, usually a vein, which traverses the macula and supplies both sides of the horizontal raphe. It is a rare condition, mostly asymptomatic and discovered on routine examination. We describe a case of both arterial and venous CRM with a macroaneurysm along the arterial CRM that presented with decreased vision due to prominent lipid exudation at the macula. Treatment with intravitreal bevacizumab resulted in a favourable anatomical as well as functional outcome. To the best of our knowledge, this is the first report of this unusual presentation of CRM, and its successful management with intravitreal bevacizumab
Assuntos
Humanos , Feminino , Idoso , Doenças Retinianas/congênito , Aneurisma , Artéria Retiniana/patologia , Bevacizumab , Injeções IntravítreasRESUMO
Giant congenital melanocytic nevus [GCMN] is a large melanocytic nevus that rarely occurs in the periorbital region. Various systemic, as well as ophthalmic associations, have been reported with GCMN. However, there is only one case report describing ophthalmic findings in periorbital GCMN. We describe the ocular findings in a case of periorbital GCMN