RESUMO
H. indicus var. pubescens [Periplocaceae] is widely distributed in southern parts of Tamilnadu, India, which is not much studied and used instead of var. indicus for its therapeutic usage. The present study evaluated the antiulcerogenic property of 50% ethanolic extracts of the roots in animal models as a muco-protective agent. Roots collected during flowering season were found to be more effective than that collected during vegetative period
Assuntos
Animais de Laboratório , Antiulcerosos , Ratos Wistar , Úlcera/terapiaRESUMO
Stem and root barks of Alangium salvifolium belonging to the family Alangiaceae were screened for their probable helicobactericidal activity. Aqueous extracts [hot and cold] and solvent extracts [acetone, chloroform and methanol] were screened. Among those, chloroform extract was observed to recover bioactive principles from the plant materials effectively. The MIC and MIC were also observed to be significantly low for human Helicobacter pylori [Hp] isolates. Samples drawn during flowering seasons were better than that of vegetative period. So the plant needs to be pursued as promising candidate in H. pylori eradication