The clinical effect of hysteroscopic IUD intrauterine surgery for inlaid incarcerated derviu / 中国基层医药

Objective To explore the clinical efficacy of hysteroscopic IUD intrauterine surgery for incarcerated ring,and to assess the safety.Methods 586 women with the incarcerated dervice remove under hysteroscope were selected in the hospital (study group),693 women during the same period used conventional methods of taking the dervice (control group ).The status of surgery,cervical relaxation,take the dervice and effect and safety were assessed.Results The operation time,amount of vaginal bleeding and take the dervice time of the study group were (19.36 ±3.14)min,(9.42 ±2.11)mL and (8.17 ±1.90)min,which were lower than those of the control group [(30.29 ±4.08)min,(15.67 ±2.38)mL and (11.35 ±2.26)min],the differences were statistically significant (t=13.16,11.51,9.76,P<0.05).The cervical relaxation goodand take part successfully of the study group were 490 cases(83.62%)and 435 cases(74.23%),which were higher than those of the control group[374 cases (53.54%)and 362 cases(52.24%)],the differences were statistically significant (χ2 =10.28,11.35,P<0.05). Waist lower abdominal pain (0-Ⅰ grade)and vaginal bleeding number (no vaginal flow or<1 day)of the study group were 509 cases (86.86%)and 362 cases (61.77%),which of the control group were 527 cases (76.05%) and 362 (46.23%),and the differences were statistically significant (χ2 =9.94,10.23,P<0.05 ).Conclusion Hysteroscopic IUD intrauterine surgery can shorten the operation time and take the dervice time,reduce the amount of vaginal bleeding and bleeding time.It can improve the success rate of taking the dervice and has fewer negative symptoms.It has high safety and clinical advantages are obvious.

Hand and wrist bone maturation in children with central precocious puberty and idiopathic short stature / 浙江大学学报·医学版

<p><b>OBJECTIVE</b>To investigate the maturation of individual bones on the hand and wrist in children with central precocious puberty (CPP) and idiopathic short stature (ISS).</p><p><b>METHODS</b>Hand and wrist films of 25 children with CPP, 29 children with ISS and 21 normal controls were evaluated by conventional Greulich-Pyle (GP) atlas method and individual bone assessment method, in which all twenty bones of the hand and wrist were evaluated based on GP atlas, including 2 radius and ulna, 7 carpal bones, 11 metacarpal and phalangeal bones, the average bone age (BA) was calculated. The differences in groups were analyzed by independent samples t test. The differences between the two methods were analyzed by paired sample t test. The differences between BA and chronological age (CA) were analyzed by ROC with SPSS 17.0.</p><p><b>RESULTS</b>Compared with the normal control group, the advance of BA in the CPP group was 0.70-2.26 y (1.48 ±0.78) by the GP atlas method, while that was 0.28-2.00 y(1.14 ±0.86) by the individual bone evaluation method. In all twenty bones, the advance of metacarpal and phalangeal BA was the greatest [0.34-2.06 y(1.2±0.86)]. In the ISS group,the delay of BA was 0.47-2.91 y(-1.69±1.22) by the GP atlas method, while that was 0.48-2.50 y (-1.49±1.01) by individual bone evaluation method.The delay of carpal BA was the greatest [0.59-2.73 y(-1.66±1.07)] in all twenty bones. In the ISS group and the normal control group, there were no statistic differences between the two methods. In the CPP group, statistic difference was found between two methods. There were no statistic differences for the areas under ROC curves between two methods.</p><p><b>CONCLUSION</b>The advance of metacarpal and phalangeal BA is the greatest in CPP group and the delay of carpal BA is the greatest in ISS group.Both methods provide diagnostic information for bone age in CPP and ISS children.</p>

Effect of 60% oxygen exposure on expression of Bax and Bcl-X_L in lungs of newborn rats / 中华围产医学杂志

Objective To investigate the effect of Bax and Bcl-X_L expression in newborn rat with moderate hyperoxic exposure. Methods Hyperoxic lung injury model was established by exposure to 60% O_2 in the neonatal period of SD rats. Rats exposed to air were used as control groups, with 8 animals in each group on repeated experiments. The pathology of pulmonary tissues was detected by HE stain. Mean alveolar area and alveolar number per ?m~2 were applied to estimate the pathological effects of prolonged hyperoxia in neonatal rats. The expression of Bax and Bcl-X_L proteins in lung were detected by immunohistochemistry and the expressions of Bax and Bcl-X_L mRNA by RT-PCR. Results In hyperoxia groups, alveolar dysplasia appeared 4 days after hyperoxia, mean alveolar area increased and alveolar number per ?m~2 decreased from the 4th day. Bax and Bcl-X_L protein were mainly expressed on bronchiolar epithelial cells and vascular endothelial cells. Compared with control group, the expression of Bax increased from the 1st day after hyperoxia, Bax mRNA decreased from the 11th day (q=8.4802, P