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Artigo | IMSEAR | ID: sea-202619

RESUMO

Introduction: Pulmonary artery hypertension (PAH) whichcan be primary or secondary, has been found to be associatedwith chronic kidney disease, especially end stage renal disease.Finding prevalence of pulmonary hypertension in early stagesof chronic kidney disease is important because it createsvery high burden of cardio vascular morbidity and mortality.In this study we have assessed various factors associatedwith prevalence of pulmonary hypertension in patients withglomerular filtration rate less than 30ml/min per 1.73 metersquare on dialysis.Material and methods: This is a one year, hospital based,prospective observational study of patients aged more than 18years with GFR less than 30 ml/min per 1.73-meter square ondialysis, who were found to have pulmonary hypertension onechocardiography. The prevalence of pulmonary hypertensionin this group of patients and the risk factors in CKD associatedwith it are calculated followed by a descriptive analysis andinterpretation of the data.Results: The various factors we analyzed and p value forassociation of pulmonary hypertension in CKD for thepercentage of male and female in our study group is 0.241, fordistribution of the pulmonary hypertension among differentage groups is 0.503, for the significance of diabetic mellitus is0.595,for systemic hypertension is 0.206, for arterial venousfistula is 0.780,for superimposed infections 0.166, for volumeoverload is 0.560, for anemia is 0.780, for left ventriculardiastolic dysfunction is 0.662, for creatinine clearance is0.717,for duration of dialysis is 0.000. With above results,only association with significant p-value (0.000) in our studypopulation with pulmonary hypertensions longer duration.Conclusion: Prevalence of pulmonary hypertension in ourstudy is 22%. The risk factors like age,sex, diabetes, systemichypertension, AVF, superimposed infection, volume overload,anaemia, LVDD has no influence on pulmonary hypertensionin our study, only strong association that we have in our studypopulation with pulmonary hypertension with CKD is longerduration of dialysis.

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