1.
Arch. med. res
;
27(1): 63-6, 1996. tab, ilus
Artigo
em Inglês
| LILACS
| ID: lil-200292
RESUMO
Histochemical and electrochemical studies were carried out on skeletal rat muscles treated with dantrolene sodium (DS) for 60 days. Histochemical experiments revealed a conversion from fast twitch (type II) to slow twitch (type I) fibers for soleus (S), gastrocnemius (GM), and extensor digitorum longus (EDL) muscles. However, a significant decreased of muscle contractility was not observed in these chronically treated rat muscles in opposition to both those directly exposed in vitro as the muscles obtained from only 1-h DS-treated animals