RESUMO
Background: Polycystic ovary syndrome [PCOS] is a frequent condition in reproductive age women with a prevalence rate of 5-10%. This study intends to determine the relationship between PCOS and the outcome of assisted reproductive treatment [ART] in Tehran, Iran
Materials and Methods: In this historical cohort study, we included 996 infertile women who referred to Royan Institute [Tehran, Iran] between January 2012 and December 2013. PCOS, as the main variable, and other potential confounder variables were gathered. Modified Poisson Regression was used for data analysis. Stata software, version 13 was used for all statistical analyses
Results: Unadjusted analysis showed a significantly lower risk for failure in PCOS cases compared to cases without PCOS [risk ratio [RR]: 0.79, 95% confidence intervals [CI]: 0.66-0.95, P=0.014]. After adjusting for the confounder variables, there was no difference between risk of non-pregnancy in women with and without PCOS [RR: 0.87, 95% CI: 0.72-1.05, P=0.15]. Significant predictors of the ART outcome included the treatment protocol type, numbers of embryos transferred [grades A and AB], numbers of injected ampules, and age
Conclusion: The results obtained from this model showed no difference between patients with and without PCOS ac- cording to the risk for non-pregnancy. Therefore, other factors might affect conception in PCOS patients
RESUMO
Background: Although leiomyomas are the most common gynecologic disorders, non-puerperal uterine inversion due to leiomyoma is considered as a rare clinical problem. This condition can occur as a complication of a large sub-mucous leiomyoma that leads to dilate cervix and protrude into vagina. The patient may have several symptoms such as heavy vaginal bleeding, pelvic pain and intermittent acute urinary retention
Case: We presented a 32-year-old nulliparous woman with 17 years of unexplained infertility and diagnosis of a large vaginal prolapsed non-pedunculated leiomyoma
Conclusion: Haultain's procedure was used to reposition uterine inversion and remove leiomyoma through a posterior incision, using laparotomy
RESUMO
Background: Threatened miscarriage is a common complication in pregnancy that leads to adverse pregnancy outcomes such as preterm labor. This study aimed to compare the vaginal progesterone [Cyclogest] versus 17-alpha-hydroxyprogesterone caproate [Proluton] on preventing preterm labor in pregnant women with threatened abortion at less than 34 weeks' gestational age
Materials and Methods: This balanced randomized, double-blind, single-center controlled clinical trial included 190 women with threatened abortion. They were then randomly allocated into Cyclogest [n=95] and 17-alpha-hydroxyprogesterone caproate [Proluton, n=95] groups. Interested outcome was preterm labor less than 34 weeks. The Pearson chi-square and Student's t test were used to compare two groups. The data were analyzed by Stata software version 13
Results: The risks of preterm labor less than 34 weeks in Proluton and Cyclogest groups were 8.6 and 6.52%, respectively. There was no significant difference for risk of preterm labor less than 34 weeks [relative ratio [RR]: 1.31, 95% confidence interval [CI]: 0.47- 3.66, P=0.59] between two groups
Conclusion: Risk of preterm labor in the vaginal progesterone group and 17-alpha-hydroxyprogesterone caproate group in pregnant women with threatened abortion is the same