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Rev. Soc. Bras. Med. Trop ; 51(4): 542-545, July-Aug. 2018. tab
Artigo em Inglês | LILACS | ID: biblio-1041473

RESUMO

Abstract INTRODUCTION This study aims to evaluate the antifungal susceptibility of different species of Candida isolated from diabetic patients against eight antifungal agents. METHODS Susceptibility testing of 111 clinical isolates of Candida species was performed against 8 antifungals using the M27-A3 protocol of the Clinical and Laboratory Standards Institute (CLSI). RESULTS Voriconazole, lanoconazole, and caspofungin showed the highest in vitro activity against all the isolates of C. albicans. Resistance against the tested antifungals was only observed in the C. albicans isolates. CONCLUSIONS Our finding revealed that resistance against amphotericin B, itraconazole, ketoconazole, posaconazole, and fluconazole can be observed in C. albicans.


Assuntos
Humanos , Masculino , Feminino , Adulto , Idoso , Idoso de 80 Anos ou mais , Candida/efeitos dos fármacos , Diabetes Mellitus/microbiologia , Antifúngicos/farmacologia , Candida/isolamento & purificação , Candida/classificação , Testes de Sensibilidade Microbiana/métodos , Pessoa de Meia-Idade
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