RESUMO
INTRODUÇÃO: O diabetes tipo 2 (DT2) pode ser responsável por disfunção cardiometabólica e redução da qualidade de vida (QV) devido ao seu impacto negativo na capacidade funcional de exercício. OBJETIVO: Investigar os efeitos de diferentes tipos de treinamento físico [treinamento intervalado de alta intensidade (TIAI) e treinamento combinado (TC)] associado à terapia com diodo emissor de luz (LED) no status cardiometabólico, capacidade funcional e QV em pacientes com DT2. MÉTODOS: Estudo controlado randomizado que será realizado em laboratório universitário de reabilitação cardiopulmonar com pessoas da comunidade com diagnóstico confirmado de DT2, idade ≥ 18 anos e sedentários nos últimos seis meses. Os participantes serão alocados aleatoriamente para um dos seis grupos: TIAI com e sem terapia LED, TC com e sem terapia LED, grupo controle com e sem terapia LED. O protocolo de treinamento deve ser realizado por 12 semanas, 3 vezes na semana em dias alternados, totalizando 36 sessões de treinamento. O desfecho primário será a capacidade de exercício e o controle glicêmico. Os desfechos secundários serão QV, função endotelial, função musculoesquelética, modulação autonômica cardíaca e composição corporal. Os resultados serão medidos antes e após 12 semanas de treinamento. Para análise estatística será utilizado o programa SPSS® 19.0. O nível de significância adotado será p<0,05. PERSPECTIVAS: Os resultados deste estudo têm o potencial de fornecer informações importantes sobre os efeitos de diferentes tipos de treinamento físico associados à terapia com LED e podem apoiar o uso dessa combinação terapêutica em pacientes com DT2, melhorando sua saúde geral.
INTRODUCTION: Type 2 diabetes (T2D) can be responsible for significant cardiometabolic dysfunction and reduction in quality of life (QOL) due to its negative impact on functional exercise capacity. OBJECTIVE: To investigate the effects of different modes of physical training (high-intensity interval training [HIIT] and combined training [CT]) associated with light-emitting diode (LED) therapy on the cardiometabolic status, functional capacity, and quality of life (QOL) in T2D patients. METHODS: A randomized controlled trial will be conducted in a university cardiopulmonary rehabilitation laboratory; the participants will be community-dwelling people with a confirmed diagnosis of T2D, aged ≥ 18 years, and with a sedentary lifestyle in the last six months. They will be randomly allocated to one of six groups: TIAI with and without LED therapy, CT with and without LED therapy, and a control group with and without LED therapy. The training protocol will be performed for 12 weeks, three times a week on alternate days, with a total of 36 training sessions. The primary outcomes will be functional exercise capacity and glycemic control. The secondary outcomes will be QOL, endothelial function, musculoskeletal function, autonomic nervous system modulation, and body composition. The outcomes will be measured before and after 12 weeks of training. SPSS® 19.0 software will be used for statistical analysis. The significance level is set at P <0.05. PERSPECTIVES: The findings of this trial have the potential to provide important insights into the effects of different modes of physical training associated with LED therapy and may support the use of this therapy combination in T2D patients, which may improve their general health.
Assuntos
Diabetes Mellitus , Controle Glicêmico , MétodosRESUMO
Abstract Objective: To compare the incidence of postoperative complications (PC) between diabetic and nondiabetic patients undergoing cardiovascular surgeries (CS). Methods: This is a retrospective cross-sectional study, based on the analysis of 288 medical records. Patients aged ≥ 18 years, admitted to the intensive care unit (ICU) between January 2012 and January 2013, and undergoing coronary artery bypass grafting (CABG) or vascular surgeries were included. The population was divided into those with and without type 2 diabetes mellitus (T2DM), and then it was evaluated the incidence of PC between the groups. Results: The sample included 288 patients, most of them being elderly (67 [60-75] years old) male (64%) subjects. Regarding to surgical procedures, 60.4% of them were undergoing vascular surgeries and 39.6% were in the postoperative period of CABG. The incidence of T2DM in this population was 40% (115), just behind hypertension, with 72% (208). Other risk factors were also observed, such as smoking in 95 (33%) patients, dyslipidemias in 54 (19%) patients, and previous myocardial infarction in 55 (19%) patients. No significant difference in relation to PC (bleeding, atrial fibrillation, cardiorespiratory arrest, and respiratory complications) between the groups was observed (P>0.05). Conclusion: T2DM has a high incidence rate in the population of critically ill patients submitted to CS, especially in the elderly. However, in this small retrospectively analyzed study, there was no significant increase in PC related to diabetes for patients undergoing CS.