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Endometriosis is a disease that most of the times is diagnosed by its common presenting sign and symptoms, but can have varied presentations and may come as a surprise during surgery. We here present a case series of unusual presentations of endometriosis, which created diagnostic dilemma and challenges in the management of the cases at this tertiary center and share our experience. Endometriosis must be kept as a differential diagnosis whenever patient presents with acute pelvic or abdominal pain with adnexal masses and things are not fitting into straight forward diagnosis.
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<p><b>INTRODUCTION</b>Paracetamol overdose is the most common drug overdose worldwide. To our knowledge, the maximum number of paracetamol tablets ingested reported in the literature is 45 g.</p><p><b>CLINICAL PICTURE</b>We describe a 21-year-old patient who acutely ingested 120 tablets, each 500 mg paracetamol (i.e., 60 g equivalent to 1200 mg/kg body weight) in a suicidal attempt. Our patient also drank 2 bottles of codeine-based cough syrup equivalent to 360 mg of codeine. At 6 hours post ingestion, her serum paracetamol level was 207 mg/L. The poor prognostic factors for paracetamol overdose in our patient included massive paracetamol ingestion (confirmed by blood levels), codeine co-ingestion and elevated serum amylase (189 U/L).</p><p><b>TREATMENT</b>She was treated with a 3-day modified regimen of intravenous N-acetylcysteine.</p><p><b>OUTCOME</b>The liver function tests and the prothrombin time remained normal over the second and third day of admission and the patient was discharged without complications on the fifth day.</p><p><b>CONCLUSION</b>From this experience we feel that in very severe paracetamol poisoning, a modified regime of intravenous N- acetylcysteine for 3 days is safe and efficacious.</p>