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1.
Pakistan Journal of Medical Sciences. 2018; 34 (6): 1525-1528
em Inglês | IMEMR | ID: emr-202007

RESUMO

Objective: To find out outcomes of cataract surgery with Microophthalmia in children less than two years


Methods: This cross-sectional study was conducted at Al-Ibrahim Eye Hospital, Karachi from January 2016 to August 2017. It included thirty micro ophthalmic eyes of infants with visually significant cataract of age less than two years who had cataract surgery without intraocular lens implantation. Axial length of globe was 19 mm or less in all thirty eyes of seventeen infants. in which thirteen infants had bilateral cataract and four had unilateral cataract


Result: Thirty Simple Micro ophthalmic eyes from seventeen patients having visually significant congenital cataract were studied. Thirteen had bilateral cataract and four had unilateral cataract. Mean preoperative IOP was 9.0 +/- 1.2 mmHg and postoperative IOP after three months was 10.9 +/- 3.2 mmHg. Three patients had secondary capsular opacification 17.6%. Two patients had posterior synachae 11.8% after three months


Conclusion: The results suggest that cataract surgery in simple microophthalmia is safe procedure. Postoperative complications in this study were within acceptable limits. Long term study with intraocular lens is required to confirm our observation

2.
Pakistan Journal of Medical Sciences. 2014; 30 (6): 1383-1387
em Inglês | IMEMR | ID: emr-148801

RESUMO

To assess the effectiveness of intravitreal injection of Bevacizumab in the treatment of diabetic macular edema. This case series was conducted at Department of Ophthalmology, Jinnah Post Graduate Medical Centre [JPMC], Karachi. The duration of study was six months from May 26, 2011 to November 25, 2011. The study group comprised of 54 patients of the Diabetic Macular Edema [DME]. Intravitreal injection of 1.25 mg of bevacizumab [Avastin] was injected 3.5 mm from the limbus under topical anaesthetic drops. Post procedure follow up was scheduled on 1[st] post procedure day and after one month. Post procedure Optical Coherence tomography [OCT] was performed in all patients 1 week before and 1[st] month after 1[st] injection. The results were statistically analyzed through SPSS 17. Out of the 54 Eyes of 54 Patients who were given the Intravitreal injection of Avastin [Bevacizumab], 43 Eyes [79.6%] showed more than ten percent decrease in macular thickness from pre-injection thickness, 10 Eyes [18.5%] showed less than ten percent decrease and 1 Eye [1.9%] showed increase in macular thickness post operatively after one month. Intravitreal injection of Bevacizumab [Avastin] is effective in the treatment of diabetic macular edema


Assuntos
Humanos , Masculino , Feminino , Anticorpos Monoclonais Humanizados , Injeções Intravítreas , Diabetes Mellitus , Fator A de Crescimento do Endotélio Vascular , Diabetes Mellitus Tipo 2 , Diabetes Mellitus Tipo 1
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