1.
Braz. j. med. biol. res
; 23(12): 1233-5, 1990. ilus
Artigo
em Inglês
| LILACS
| ID: lil-103649
RESUMO
Rabbit and, to a lesser extent, human immunoglobulins (IgGs) are cleaved by snake venoms. The snake venom proteases active on IgGs release fragments which behave on SDS-PAGE like Fab units similar to those release by the thiol-activated enzymes. However, in contrast to the cysteine proteases, the activity of snake venom proteases on IgGs is not only blocked by metal chelating agents but is also inhibited by thiol compounds. The snake enzymes active on IgG are metalloproteases
Assuntos
Coelhos , Ratos , Animais , Humanos , Fragmentos Fab das Imunoglobulinas/metabolismo , Imunoglobulina G/metabolismo , Venenos de Serpentes/metabolismo , Eletroforese em Gel de Poliacrilamida , Peptídeo Hidrolases/metabolismo , Venenos de Serpentes/enzimologia
2.
Braz. j. med. biol. res
; 18(3): 337-40, 1985. ilus
Artigo
em Inglês
| LILACS
| ID: lil-27418