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Scientific Journal of Al-Azhar Medical Faculty [Girls] [The]. 2000; 21 (Supp. 1): 1231-1246
em Inglês | IMEMR | ID: emr-55675

RESUMO

This study was performed on 40 type I diabetes [IDDM] patients with complications [nephropathy and retinopathy], 20 IDDM patients without complications and 20 age and sex matched healthy control subjects. IDDM patients with complications had significantly higher fasting total homocysteine [tHCY] and endothlin-1 [ET-1] plasma levels than the other two groups. In diabetic patients without complications, plasma tHCY had a slight increase than the control subjects, while plasma level of ET-1 was significantly higher than the control subjects. tHCY plasma level was correlated with albumin excretion rate [AER], serum creatinine and ET-1 glycated hemoglobin [HbA1c], but it was not correlated with the duration of diabetes mellitus, serum lipids and age of the patients


Assuntos
Humanos , Masculino , Feminino , Homocisteína/sangue , Endotelina-1/sangue , Nefropatias Diabéticas , Retinopatia Diabética
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