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1.
Benha Medical Journal. 2008; 25 (2): 135-148
em Inglês | IMEMR | ID: emr-112119

RESUMO

Suppurative otitis media is a common disease affecting all ages and both sexes. Development of bacterial resistance is very common making difficulties in management of both acute suppurative otitis media [Ac s o m] and chronic suppurative otitis media [Ch s o m] cases. More recently, interest in honey as a therapeutic agent has undergone a renaissance. Honey is used for management of infected wounds, burns and exhibited excellent results against Gram +ve and Gram-ve organisms in vitro and in some in vivo studies on infected wounds. To compare results of using Al-sidr honey and antibiotics for treatment of acute and chronic suppurative otitis media. Culture and sensitivity of honey, using agar incorporation technique to prepare plates containing serial dilutions of honey to detect MIC for the selected organisms. Preparing honey as ear drops 10% more than MIC. One hundred twenty patients, 60 with [Ac s o m] and 60 with [Ch s o m] divided into 2 groups, Group 1 honey group divided into Group 1A: 30 patients with ac s o m [10 with Streptococcus pneumonia, 10 with Haemophilus influenza and 10 with Moraxtila catarrhalis] and Group IB 30 patients with ch s o m [10 with Pseudomonas aeroginosa, 10 iuith KLebsiella and 10 with Proteus] treated by Al-sidr honey local ear drops. Group 2 antibiotic group same distribution as group 1 and treated by antibiotics. There is significant differences between using honey and traditional approach for antibiotic use even after CIS without side effects or complications. We recommend start thinking to use Al-sidr honey as local ear drops for management policies of suppurative otitis media


Assuntos
Humanos , Masculino , Feminino , Mel , Antibacterianos , Resultado do Tratamento , Otite Média Supurativa/microbiologia , Gerenciamento Clínico
2.
Benha Medical Journal. 2008; 25 (2): 149-160
em Inglês | IMEMR | ID: emr-112120

RESUMO

Peritonstilar infection describes a spectrum of diseases that range from peritonsillar cellulitis to peritonsillar abscess. To assess the disease pattern and its management and to examine the role of routine bacterial cultures. We carried out a prospective study with 30 patients diagnosed with peritonsillar infection. Twenty two patients with peritonsillar abscess [PTA] and eight cases with peritonsillar cellulitis [PTC] of these eight cases 4 cases resolved with medicine and the other 4 cases progressed to [PTA] so finally we have 26 cases with [PTA], for these needle aspiration is done from the most prominent point and if pus came we progressed to incision and drainage wider local or general anesthesia according to patients condition. Around 3ml of pus is taken and sent to lab. Immediately and processed for culture for aerobic and anaerobic organisms. Then these 26 cases of PTA divided into 2 groups each one contains 13 cases group I received ampicillin plus metronidazole and group 2 received 3rd generation cephalosporins plus metronidazole. We assessed number of bacteria per aspirate as well as type of bacteria present aerobic or anaerobic. After results of c/s came we assessed the need to change antibiotics. Lastly we assessed length of stay in the hospital for both groups according to antibiotics used. We found 2.1 bacteria per aspirate. Bacteria grown from all aspirates with culture positivness 100%. We found 55 bacteria grown from 26 cases of PTA, with 28 aerobes and 27 anaerobic organisms. There were need to change antibiotics in 3 cases of group I and in 5 cases of group 2 with significant difference. Mean length of stay in group 1 was 4 +/- 3 while in group 2 was 5 +/- 2 with non significant differences between both groups. 1-Culture and sensitivity of pus drained from PTA should be done. 2-We should use drugs for anaerobic organisms on treatment of peritonsillar infections


Assuntos
Humanos , Masculino , Feminino , Biópsia por Agulha Fina , Técnicas de Cultura , Testes de Sensibilidade Microbiana , Abscesso Peritonsilar/terapia , Cefalosporinas , Metronidazol , Resultado do Tratamento
3.
Benha Medical Journal. 2005; 22 (2): 43-58
em Inglês | IMEMR | ID: emr-202259

RESUMO

This study was designed to evaluate the volumetric reduction and the histologic changes of the soft palate after coblation [cold ablation] technology in experimental animals. Sixty male rabbits were included in the study divided into 3 groups: group [A], group [B] and group [C]. Each group included 10 control and 10 study animals. Exposure of the soft palate to coblation was done in study animals of the 3 groups submucosaly at 3 sites, one at midportion and 2 at lateral sides of the soft palate for one minute duration in each site. The control animals of the 3 groups were left without any interference. The animals of group A. B and C were studied 1 month, 2 months and 3 months respectively. The soft palate of each rabbit was dissected and volume was calculated. Specimens of soft palate of both control and study animals were examined by electron microscopic study. Died animals were excluded from this study. The comparison of the mean volume of soft palate in the study groups showed gradual increased reduction with time as it was more after 3 months [group C] than 2 months [group B] and 1 month [group A]. This result was confirmed by electron microscopic study as there was an increase in the amount of collagen fibers in the subepithelial layer gradually in study groups which was mild, moderate and marked in group A. B and C respectively. Cytoplasmic vacuoles were detected more in the epithelial layer of study group [A] than group [B] this means degenerative changes which is reversible as it was decreased by time and disappeared in group [C]. There is no effect on the mucosal glands of the epithelium or underlying muscles. The only histological difference between study and control groups was the increased amount of collagen fibers in the subepithelial layer. Coblation technology could be considered an effective technology for the reduction of the size of soft palate. It is safe, not painful and not invasive as it maintain the normal histology of the soft palate

4.
Zagazig University Medical Journal. 2000; 6 (7): 1245-1256
em Inglês | IMEMR | ID: emr-56061

RESUMO

The authors repored six cases of atypical osteomyelitis of the skull base in diabetic patients. They were studied clinically, radiologically and pathologically. This disease may arise without initial temporal bone affection or may complicate incompletely treated malignant otitis externa. Spread of the disease may occur through vascular involvement of the skull bones and facial planes rather than through the air cells. The ethmoid, the sphenoid and occipital bones are affected besides the temporal bones and the petrous apex. Multiple cranial nerves may be affected including the 2nd, 3rd 4th 5th 9th and 10th nerves and the disease may present as the jugular foramen or the orbital apex syndromes. The morbidity and the mortality of the disease is higher in patients without previous temporal bone affection because it is usually not promptly recognized and treated


Assuntos
Humanos , Masculino , Feminino , Base do Crânio/complicações , Nervos Cranianos , Manifestações Neurológicas , Tomografia Computadorizada por Raios X , Diabetes Mellitus , Radioisótopos de Gálio
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