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Indian J Pathol Microbiol ; 2010 Jul-Sept; 53(3): 548-550
Artigo em Inglês | IMSEAR | ID: sea-141743

RESUMO

We report the simultaneous occurrence of the tall cell variant of papillary carcinoma and squamous cell carcinoma in the thyroid gland. Histology and immunohistochemical findings are discussed and it seems that the malignant squamous component was transformed from the tall cell variant of papillary carcinoma. Metastasis from the squamous cell carcinoma is diagnosed in the regional lymph node.

6.
Indian J Med Microbiol ; 2008 Jul-Sep; 26(3): 252-5
Artigo em Inglês | IMSEAR | ID: sea-53776

RESUMO

This study examined the incidence of human herpes virus-6 (HHV-6) and human cytomegalovirus (HCMV) infections that are potentially transmitted to haematopoietic stem cells (HSC) transplant recipients via bone marrow (BM) or umbilical cord blood (UCB). Bone marrow progenitor cells were collected from 30 allogenic BM donors. UCB HSC were collected from 34 subjects. The extracted DNA was then processed using nested polymerase chain reaction (nPCR) technique. HCMV and HHV-6 serological status were determined by enzyme immunoassay (EIA). Nested PCR identified HCMV in 22 (73%) of 30 samples of BM progenitor cells but in only eight (23.5%) of 34 samples of UBC HSC ( P = 0.001). HHV-6 DNA was detected in 11 (36.6%) of 30 BM progenitor cells and in only one (2.9%) of 34 UBC cells ( P = 0.002). Both HHV-6 and HCMV infections were determined in nine (26.5%) of 34 bone marrow samples. The results indicate that, the risk of HCMV and HHV-6 via BM progenitor cells is higher than transmission by UCB cells ( P= 0.04).


Assuntos
Adulto , Anticorpos Antivirais/sangue , Citomegalovirus/genética , Infecções por Citomegalovirus , DNA Viral/genética , Feminino , Herpesvirus Humano 6/genética , Humanos , Técnicas Imunoenzimáticas , Incidência , Masculino , Reação em Cadeia da Polimerase , Infecções por Roseolovirus/epidemiologia
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