[10-year graft survival analysis of renal transplantation and factors affecting it in patients transplanted from live donor in Shiraz transplant research center during 1999-2009]

Background and Aims: Renal transplantation is the best therapeutic option for End Stage Renal Disease [ESRD]. The aim of this study was to determine the graft survival rate of renal transplantation in patients who have been transplanted from live donor in Shiraz Transplant Research Center, Shiraz, Iran

Methods: In a survival analysis study, organ survival rate after kidney transplantation from live donor was determined in 843 patients being transplanted in Shiraz Transplant Research Center, Iran during a period of 10 years [March 1999 to March 2009]. Kaplan-Meier method was used to determine the survival rate, Logrank test was used to compare survival curves and Cox proportional hazard model was used for multivariate analysis

Results: Mean follow-up period [+/- Standard deviation] was 53.07+/-34.6 months. Allograft survival rates at 1, 3, 5, 7 and 10 years after kidney transplantation were found to be 98.3%, 96.4%, 92.5%, 90.8% and 89.2%, respectively. Using Cox proportional hazard model, age of donor and creatinine level at discharge showed significant relationships with survival rate of renal allograft

Conclusion: The 10- year graft survival rate of renal transplantation from live donor in this center is 89.2% which in comparison with reports from large centers of transplantation it is satisfactory

Estimation of survival and factors related to it in Esophageal Cancer using actuarial life-table mathod

Esophageal cancer is the 6th common cancer in Iran. Affected patients have a relatively short lifetime, as this cancer is usually diagnosed in advanced stages. This study was conducted to estimate survival and factors related to it in patients with esophageal cancer. All patients definitely diagnosed as esophageal cancer, registered in Fars Cancer Registry Center, were investigated. Required information was gathered from cancer registry forms and other resources. 1- to 5-year survival rates were estimated using life-table method. Wilcoxon test was used to compare survival rates between subgroups. All data were analyzed by SPSS software. Of 161cases, 61.5% were male. Mean age of patients was 64.6 +/- 13.10 years and 57.6 +/- 11.9 years in male and female, respectively. Overall survival rates at 1- to 5-years after diagnosis were: 58, 33, 18, 15 and 9 percent, respectively. Factors such as age at time of diagnosis, Presence of metastasis, histologic grade, type of first treatment, occupation in males, ethnicity and number of household showed to have a significant effect on prognosis. According to this study and similar studies carried out, screening and early detection of patients [in lower ages, and lower stages] is emphasized

[Quality of life and related factors in breast cancer patients under chemotherapy]

Today, the quality of life study has an important role in health care especially in chronic diseases, in clinical judgment and in medical resources supplying. Malignancies have a clinical and health importance in the world and Iran. Breast cancer has first order among women's malignancies. Now, survival rate for this cancer is long. However Breast cancer has several complications that affected patient's life. It is necessary that we studying the quality of life and related factors among this patients. We conducted a cross-sectional study on 119 breast cancer patients that admitted and treated in chemotherapy ward of Namazi hospital in Shiraz.We used QLQ-C30 and QLQ-BR23 to assessment quality of life in these patients. We used univariate nonparametric tests and multiple linear regression model to identify associations between dependent variables and the quality of life and it's different scales.All calculation performed by using SPSS.V.13. Mean age of patients was 48.27 +/- 11.42 with quality of life total score 64.92 +/- 24.28. Univariate analysis showed that occupation,duration of disease,grade of tumor, physical, emotional and cognitive functioning, also, symptoms such as fatigue,pain, nausea and vomiting, insomnia, constipation and financial difficulties, perspective were associated to quality of life. [P< 0.05]. But in multivariate analysis, only occupation, menopause status, dyspnea, grade of tumor and financial difficulties perspective were related to quality of life [p<0.05]. With this finding, It is recommended that financial supports, also early detection are necessary for improvement of quality of life in these patients

Some risk factors of obesity in rural women of Zarrindasht: using linear regression odds ratio

Obesity is becoming a world wide health problem, affecting all groups of age, sex and economy. This important problem is a major risk factor for some diseases. The prevalence of obesity not has been well studied in the rural areas. The purpose of this study was to determine the prevalence of obesity and some of the relevant risk factors in women of Zarrindasht rural areas using the odds ratio estimated from the regression approach. In a cross-sectional study in 2005, a number of 920 women infertility age from rural areas of Zarrin-Dasht, at eastern part of Pars province were selected by random multi stage sampling. Correlation ship between BMI and some variables including age, education level, number of children, socio-economic status and mean duration of breast feeding were evaluate. The age and education level of their husbands were also considerved. Odds ratio [OR] was using both logistic regression approach and the linear regression procedure [without dichotomizing]. BMI of 25 or higher was considered as over weight or obesity. The studied women aged between 17 to 47 years old and the prevalence of over weight [25/= 30] was 30% and 14% respectively. In both statistical models, significant associations were found among husbands education, number of children, socio-economic status and increasing risk of obesity. Precision of linear regression approach in estimating OR was higher than that of logistic regression. It is concluded that, similar to the urban areas, the obesity is highly prevalent in the rural population. This can potentially affect the health of rural community and needs consideration. Prevention and control of obesity are recommended to be as of health program priorities

[Correlation between academic achievement and introversion-extroversion and neuroticism of nursing students in Shiraz]

Background: Survey on the factors influencing the student's academic achievement, who are the most intelligent people is important

Objective: This study was performed in order to determine the relationship between academic achievement and personality of students

Methods: This is an analytic study. Subjects consisted of 304 full time undergraduate nursing students [total students] at Fatemeh [P.B.U.H] college in second semester of 1999-2000 [academic year]. The subjects were assessed by a demographic questionnaire, Eysenck's personality Inventory and total average of grades as academic achievement. Data analysed using the t-test, analysis of varivance and pearson correlation

Findings: Mean score in introversion was 12.41 and in neuroticism 12.10. 25.5% of students were successful in studying and 25% were unsuccessful and others were moderate. There was a significant negative correlation between academic achievement with neuroticism [-0.1171, P=0.045]

Conclusion: According to the findings, student's mental condition had effects on their academic achievement. The follow up of student's mental health and personality and activation of mental consultation centers for them is necessary