Acute pyogenic meningitis; incidence in paediatrics [in infants and children]

118 cases of acute pyogenic meningitis were admitted in the department of Paediatrics Liaquat Medical College, Hospitals Jamshoro/Hyderabad in one year period with prevalence of 1.57% of the total admissions. After selecting the cases on clinical ground we proceeded further to confirm the diagnosis by cerebrospinal fluid cytochemical analysis, gram staining, culture and sensitivity and detection of the antigen of micro-organism by latex agglutination test

Mortality and morbidity of 118 cases of acute pyogenic meningitis in paediatrics age group

One hundred eighteen cases of acute pyogenic meningitis were admitted in the department of paediatrics Liaquat Medical college Hospitals Jamshoro/Hydrabad during one year period with a prevalence of 1.57% of total admissions. Thirty one were neonates and 87 were of post neonatal age group. Gram negative micro-organisms responsible for [66/118] 55.93% of cases with high fatality rate, whereas E.coli was responsible 13/31 [41.93%] in neonates with fatality rate of 58.33% [7/12]. In post neonatal period streptococcus pneumoniae responsible for 31/878 cases with fatality rate of 44% [11/25], and H.influenzae prevalence was 17.24% with fatality rate of 28% [7/25] and Niseria meningitidis was responsible for 28.73% [25/87] cases with fatality rate of 8% [2/25]. The overall fatality rate [mortality + morbidity] was 31.35% [37/118] various factors responsible for fatality are poor nutritional status, delay in referring the cases and to start of optimal therapy, lack of prompt laboratory aids for identifi cation and sensitivity of micro-organisms, the modified clinical pictures as a result of inadequate treatment before admission

Clinical response with antibiotics of 37 cases of acute pyogenic meningitis in paediatrics [from 3-12 years]

Over a period of one year 37 confirmed cases of acute pyogenic meningitis by latex agglutination method were admitted in department of paediatrics, Liaquat Medical College Hospitals [LMCH] Jamshoro Hyadrabad, Sindh. These patients were treated with various antibiotics with the result that ampicillin plus chloromycetin is in combination as is effective as cephalosporin up to the age of 4 years and up to 12 years ampicillin as ampicillin plus chloromycetin which is standard treatment

Incidence of acute pyogenic meningitis in infants and children

118 cases of acute pyogenic meningitis were admitted in the department of Paediatrics Liaquat Medical College, Hospitals Jamshoro/ Hyderabad in one year period with prevalence of 1.57% of the total admissions. After selecting the cases on clinical ground were proceeded further to confirm the diagnosis by cerebrospinal fluid cytochemical analysis, gram staining, culture and sensitivity and detection of the antigen of micro-organism by latex agglutination test