Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Adicionar filtros








Assunto principal
Intervalo de ano
1.
Pakistan Journal of Pharmacology. 1986; 3 (1-2): 57-65
em Inglês | IMEMR | ID: emr-7983

RESUMO

Pharmacokinetic parameters which describe distribution and elimination of oxytetracycline were determined in 8 dogs. Following intravenous administration of a single dose [7.5 mg/kg], the disposition of the drug was described in terms of biexponential expression: Cp = Ae-alpha t + Be-beta t. The pseudo-distribution equilibrium was rapidly attained and the half-life for elimination was 17.3 +/- 4.2 h [average +/- SD]. Body clearance which is sum of all clearance processes, was 126.5 +/- 28 ml/kg/h. Based on these findings, intravenous dosage regimen at different time intervals was calculated. The influence of disease conditions on the predicted plasma levels remains to be verified


Assuntos
Cães
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA