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Indian J Lepr ; 1993 Oct-Dec; 65(4): 423-7
Artigo em Inglês | IMSEAR | ID: sea-55138

RESUMO

A study was made on Langerhans cells (LC) in the dermal lesions of leprosy after epicutaneous application of 2:4 dinitrochlorobenzene (DNCB) to the lesion. LC were quantitated with OKT6 monoclonal antibody and indirect immunofluorescence. A depletion or reduction in the numbers of CD1+ epidermal LC was observed at both 4 and 24 hours after the application of DNCB in the lesions of both tuberculoid and lepromatous leprosy, compared to untreated lesions.


Assuntos
Administração Cutânea , Anticorpos Monoclonais , Contagem de Células/efeitos dos fármacos , Dinitroclorobenzeno/uso terapêutico , Humanos , Células de Langerhans/efeitos dos fármacos , Hanseníase Virchowiana/tratamento farmacológico , Hanseníase Tuberculoide/tratamento farmacológico
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