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1.
Pakistan Journal of Medical Sciences. 2017; 33 (1): 177-181
em Inglês | IMEMR | ID: emr-185500

RESUMO

Background and Objective: Pain control during surgery in order to cause analgesia and reduce the somatic and autonomic response may decrease the morbidity. Intrapleural catheter embedding during surgery under direct vision of surgeon is safe and easy and without potential risk of thoracic epidural block. The aim of this study was to investigate the effect of bilateral intrapleural infusion of lidocaine with fentanyl versus only lidocaine in relieving pain after coronary artery bypass surgery


Methods: In this prospective randomized double blind clinical trial,130 adult patients undergoing elective CABG with age range of 20 to 60 years were divided into two groups receiving either lidocaine and fentanyl [group A] or lidocaine [group B]. The analgesia was evaluated every two hours in all intubated and non-intubated patients using Visual analog scale [VAS] and data were analyzed using SPSS software package


Results: Of all patients, 67 [51.5%] were males and 63 [48.5%] were females. The average age of subjects was 53.49 +/- 5.099 years. Mean pain score six hours after the surgery was statistically different between the groups at all times


Conclusion: The pain in patients receiving combination of lidocaine and fentanyl is less than patients receiving only lidocaine

2.
Pakistan Journal of Medical Sciences. 2016; 32 (4): 900-904
em Inglês | IMEMR | ID: emr-182502

RESUMO

Objective: Atrial fibrillation is the most common arrhythmia after cardiac surgery. Several studies have shown the impact of vitamin D on heart disease; however, there have been few studies for the incidence of AF and its relationship with vitamin D levels. According to the different results of these studies, we decided to evaluate the relation of plasma levels of vitamin D and postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery [CABG]


Methods: This cross-sectional study was performed on 50 patients after CABG surgery. Simple random sampling was done. Twenty five patients who developed AF within 48 hours after CABG with Cardiopulmonary bypass [CPB] were enrolled in the case group and 25 patients who did not develop AF within 48 hours after CABG with CPB were enrolled in the control group. Plasma levels of vitamin D in both groups of patients were recorded. Collected data were analyzed by the SPSS software version 17


Results: There was no significant difference in terms of demographic characteristics, comorbidities, lipid profile and kidney function between two groups. The mean plasma level of vitamin D was 27.4 +/- 2.22 ng/ ml in the case group and was 28.2 +/- 1.18 ng/ml in the control group it [p= 0.803]


Conclusions: Plasma levels of vitamin D were almost the same in both groups and there was no statistically significant difference between the groups with and without atrial fibrillation following CABG

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