Comparison of Basement Membrane in Normotensive and Pregnancy Induced Hypertensive Placentae

Introduction: Placenta is related to mother and foetus viaindirect interaction with maternal blood that spurts out ofuteroplacental vessels. By study of placental bed newinformation has come to light, especially for pre – eclampsiaand intra uterine fetal growth retardation.Aim: To study changes in basement membrane in pregnancyinduced hypertensive and normotensive placentae.Materials and Methods: The present study was conducted inthe Department of Anatomy, MMMCH, Kumarhatti, Solan tostudy the histological changes in placenta in pregnancyinduced hypertensive parturients as compared to normotensivesubjects. It was based on 100 cases, 25 from normotensivesubjects (control group) and 75 from clinically proven cases ofpregnancy induced hypertension (study group).An attempt was made to see any changes in histologicalfeatures of placentae of pregnancy induced hypertensive casesand compare it with normotensive placentae.Results and Conclusion: The microscopic study showedsignificant thickening of basement membrane in PIH placentae.As compared to normotensive placentae (control) and are dueto occlusion or narrowing of utero placental vasculaturesuggesting thereby compromised foeto – placental circulation.

Athersclerosis in coronaries in Malwa Region of Punjab.

The study involves the gross and microscopic examination of coronary arteries of 200 cases of all age groups brought to mortuary of Rajindra Hospital Patiala for post mortem from Malwa Region of Punjab. The study was carried out to find out prevalence, pattern, frequency and severity of atherosclerotic changes in coronary arteries. The study was conducted in the department of Forensic Medicine and Department of Pathology Government Medical College Patiala.

Pathological findings in liver autopsy.

Liver is the site of many diseases, many of which become symptomatic while some are diagnosed only on autopsy. Involvement of liver is secondary to cardiac, metabolic and social problems like alcoholism. In this autopsy study of one hundred cases of liver specimens, fatty change, venous congestion, cirrhosis of liver, malignancy, hepatitis and chronic abscess are reported; fatty change being the predominant finding.

Fibrous histiocytoma of orbit: a case report.

A fifty year male (K.S.) presented with protrusion (Proptosis) of left eye which was gradually increasing in size for the last one year. The swelling was accompanied by pain for the last fifteen days. Preoperative X-ray & computed tomography showed erosion of frontal sinus & roof of maxillary sinus. Clinical diagnosis of a malignant tumour of eye was made & enucleation of the left eye, along with the mass was done. The specimen was received in the pathology department on 16.9.98. Grossly, encapsulated mass attached with the intact eye ball was received. The mass measured 5x3x2.5 cms. Microscopic examination revealed a benign spindle cell neoplasm and a diagnosis of fibrous histiocytoma (dermatofibroma) was made.

Myelolipoma of adrenal gland in association with occult malignancy--a case report.

Myelolipoma is an unusual lesion of adrenal gland in which ectopic marrow tissue is present. This case is being present because of its rarity.