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Renal cell carcinoma (RCC) is heterogeneous disease which is having different histological variants with a distinct clinical course and genetic changes. Papillary renal cell carcinoma is an uncommon variant of renal cell carcinoma. It is considered to be a less aggressive tumour. This tumour has better prognosis than that for non-papillary renal tumours. As the prognosis of Papillary RCC depends upon early detection and typing of the RCC, meticulous histopathological examination of nephrectomy specimen is must.
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Introduction: Cervical cancer is the third most common type of cancer among women worldwide, following breast cancer and colon cancer. The micronucleus test is a simple and widely used technique to evaluate genetic damage due to exposure to carcinogenic or mutagenic agents. We undertook this study to compare the MN (micronucleus)score in the whole spectrum of cervical lesions Materials and methods:In this retrospective study, we had compared the MN score in the whole spectrum of cervical lesions which comprised of seven different groups like normal (20), inflammatory (30), ASC-US (20), ASC-H (13), LSIL (20), HSIL (10) and IC (19) over aperiod of 1year (January 2014 to December 2014)which includeda total of 132 cases.Results:In the present study,there was a stepwise gradual increase in MN count from inflammatory to ASC-US to LSIL to HSIL group, followed by a slight increase in IC. The mean MN count was most significant in the LSIL and HSIL group. Thus micronucleated cells as well as the total number of micronuclei show increasing trend towards malignization.Conclusion:Our study showed that MN counting can be a helpful screening tool in conjunction with conventional Pap test for screening of cervical cancer.
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Introduction: Breast carcinomas are one of the leading causes of cancer in women. Fine Needle Aspiration Cytology (FNAC) is one of the important tools for the pre-operative diagnosis of breast lesions. Materials and methods: A total of 200 breast aspirates were studied. Histo-cytopathological correlations were obtained in all cases. All the aspirates were stained with Hematoxylin and Eosin (H and E) stain. Results: Among 200 patients, 195 were females and 5 were males. Benign breast lesions were found in 120 cases; among which fibroadenoma (34%) was the commonest lesion which was observed. Malignancy was observed in 80 cases; among them, ductal carcinoma was the predominant. Conclusion: We can conclude that FNA is widely accepted as a reliable technique in the initial evaluation of palpable breast lumps. It is simple, safe, cost-effective, minimally invasive, rapid and as sensitive as biopsy.