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Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (24): 1090-1093, 2015.
Artigo em Chinês | WPRIM | ID: wpr-747265

RESUMO

OBJECTIVE@#To study the therapeutic effects of the specific immunotherapy (SIT) on allergic rhinitis and allergic rhinitis combined bronchial asthma. METHED: All patients were classified into allergic rhinitis group (AR group) with 32 patients and allergic rhinitis combined bronchial asthma group (AR+BA group) with 32 patients. Another health control group with 32 cases was designed as well. The allergens,symptom scores and therapeutic effects of the former two-group patients were analysis, and the serums of all three-group cases were extracted to evaluate the specific Immunoglobin E(sIgE), Interleukin-4 (IL-4). The SPSS13. 0 package was applied to conduct t-test and chi-square test, and the difference of P<0. 05 was regarded as statistical significance.@*RESULT@#The main allergens of 64 patients were dermatophagoides farinae and dermatophagoides pteronyssinus. The improvement of symptom scores before and after SIT was statistical significant with P<0. 05. Although total effective rate reached 100% , AR group was superior than AR+BA group in term of the efficacy comparison, and P<0. 05 indicated the statistical significance. The serum sIgE, IL-4 values of three groups were brought into comparison, and P<0. 05 indicated the statistical significance of the difference.@*CONCLUSION@#The SIT on the AR, AR+BA is a safe and effective treatment, but different disease responds diversely. The long-term treatment course is recommended.


Assuntos
Animais , Humanos , Alérgenos , Alergia e Imunologia , Asma , Terapêutica , Dermatophagoides farinae , Alergia e Imunologia , Dermatophagoides pteronyssinus , Alergia e Imunologia , Imunoglobulina E , Sangue , Imunoterapia , Interleucina-4 , Sangue , Rinite Alérgica , Terapêutica , Resultado do Tratamento
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