RESUMO
ObjectiveTo investigate the clinical value of Longbeisan application at Shenque （CV 8） combined with oral administration of Chinese medicine in the treatment of premature ejaculation （PE）. MethodA total of 98 PE patients treated in the andrology department of the First Affiliated Hospital of Henan University of Chinese Medicine at the same time period were randomly assigned into an observation group and a control group， with 49 patients in each group. The observation group received Longbeisan application at Shenque （CV 8） combined with oral treatment of Chinese medicine according to syndrome differentiation， and the control group was treated with dapoxetine hydrochloride tablets. The treatment in both groups lasted for 8 weeks. The intravaginal ejaculatory latency time （IELT）， Chinese index of premature ejaculation-5 （CIPE-5） score， patient's sexual life satisfaction， spouse's sexual life satisfaction， effective rate， and adverse reaction incidence were compared between the two groups. ResultAfter treatment， the observation group had higher total effective rate than the control group ［（85.71% （42/49） vs. 67.35% （33/49）， χ2=6.262， P<0.05］. The IELT， CIPE-5 score， and patient's and spouse's satisfaction scores after treatment increased compared with those before treatment （P<0.01）， and the increases were more significant in the observation group （P<0.05， P<0.01）. The clinical effect of the observation group was better than that of the control group. During the treatment， 7 （7/49，14.29%） patients in the control group and 2 ，2/49，4.08%） patients in the observation group showed adverse reactions， which indicated the safety of the observation group was better than that of the control group （χ2=9.000， P<0.05）. In the follow-up period， 11 （11/49，22.45%） patients in the control group and 3 （3/49，6.12%） patients in the observation group showed aggravation of symptoms， which meant that the observation group had better lasting effect （χ2=0.317， P<0.05）. ConclusionLongbeisan application at Shenque （CV 8） combined with oral administration of Chinese medicine has better clinical effect， stronger safety， and longer effect than dapoxetine hydrochloride in the treatment of PE.
RESUMO
Through observation on changes of inflammatory mediators and hemorrheology among chronic prostatitis patients before and after treatment, this study was aimed to compare the therapeutic differences between the applications of standard retention enema ofQu-Yu Tong-Bi (QYTB) decoction andα-blockers combined with quinolones. During the same period, 164 patients of the Henan Province of Traditional Chinese Medicine Hospital were randomly divided into the observation group and control group, with 62 cases in each group. Retention enema of QYTB decoction was given in the observation group; andα-blockers combined with quinolones were used in the control group. The treatment course was one month. And the differences were compared. The results showed that the total effective rate of the observation group was 79.03% (49 cases); and that of the control group was 61.29%(39 cases). There was statistical significance between two groups (P < 0.05). There was statistical significance on TNF-α, IFN-γ and NIH-CPSI score comparison before and after treatment of two groups (P < 0.05). Compared to the control group, the posttreatment TNF-α, IFN-γ and NIH-CPSI score in the observation group had significant difference (P < 0.01). There were no significant differences on the whole blood viscosity (high shear), plasma viscosity and erythrocyte deposited test value contrast between pretreatment and posttreatment in the control group. There were significant differences on the whole blood viscosity (high shear) and plasma viscosity between pretreatment and posttreatment in the observation group (P < 0.05). However, there was no significant differences on erythrocyte deposited test value contrast. It was concluded that both methods had certain therapeutic effect in the treatment of chronic prostatitis. However, the effect of retention enema of QYTB decoction was better than the treatment of quinolones combined withα-blockers.
RESUMO
OBJECTIVE:To observe the curative effect of relinqing granule on patients with chronic prostatitis of damp-heat type.METHODS:200patients with chronic prostatitis of damp-heat type were divided into treatment group(relinqing granule+norfloxacin capsules)and control group(norfloxacin capsules)at random.RESULTS:The total effective rates of the treatment group and the control group were92%and52%(P