RESUMO
OBJECTIVE:To investigate the use of antibacterials and to evaluate the distribution and drugs resistance of pathogenic bacteria causing hospital nosocomial infection between 2005 and 2007 in our hospital. METHODS:The antibiotic resistance and the data of drug use from 2005 to 2007 in our hospital were analyzed statistically. RESULTS:Over the 3 years,the production rate of ESBLs of Escherichia.coli ascended year by year. The proportion of methicillin resistant staphylococcus aureus (MRSA) in staphylococcus aureus were 79.4%,66.3% and 73.9% respectively over the 3 years. The DDDs of antimicrobials showed an year-on-year increase,with third-generation cephalosporins and fluoroquinolones topping the first two places. CONCLUSION:Antibacterial drugs should be used rationally in clinical practice so as to reduce antibiotic resistance.
RESUMO
OBJECTIVE: To provide meaningful reference for the improvement of full-time clinical pharmacists' ability.METHODS: According to clinical practices,the experience of author engaging in clinical pharmacy was introduced.RESULTS & CONCLUSION: Clinical pharmacists should take a correct attitude and practice their profession as best as they could,based on the professional orientation.Scientific research should be linked with problem settlement to promote the growth of clinical pharmacists.
RESUMO
OBJECTIVE:To evaluate the cost-effectiveness of3Chinese and western medicines in treating senile func?tional constipation.METHODS:186patients with senile functional constipation were randomly assigned to receive Forlax powder preparation for infusion,Liuweianxiao capsule and Buzhongyiqitang respectively,the therapeutic efficacies of the3groups were observed and the cost-effectiveness analysis were conducted12weeks after treatment.RESULTS:The cure rates for the3groups were77.6%,83.3%and85.5%,respectively;the costs for the3groups were963.52yuan,877.00yuan and850.12yuan,respectively;the ratio of cost to effectiveness were1241,1052and975,respectively;the incremental cost-effectiveness ratio of Group A and B were1435and1221as compared with Group C.CONCLUSION:Liuweianxiao capsule(Group B)was the preferred option for the treatment of senile functional constipation.
RESUMO
OBJECTIVE:To prepare compound astragali capsules and to establish its quality control standards.METH?ODS:The qualitation identification of the principal agents like American ginseng and asiatic cornelian cherry fruit were de?termined by TLC;the principal agent-astragalosideⅠin the astragali were identified by HPLC-ELSD.RESULTS:The condition for TLC qualitation was feasible and the spots were clear;good linear relationship was achieved when the detection concentration of astragalosideⅠwas within the range of2.8?g～8.4?g(r=0.9999);the average recovery was99.93%,RSD=1.17%.CONCLUSION:The preparing technique of this preparation was simple and the quality was stable,the quan?titation control method is simple,accurate and with high precision.
RESUMO
0.05), respectively; the costs of topiramate or sodium valproate retard tablets were 1 305.00 yuan and 588.60 yuan, respectively. CONCLUSION: Sodium valproate retard tablet is superior to topiramate tablet in terms of cost - effectiveness.
RESUMO
0.05),and the total medical costs were 15 924.36 yuan,12 018.36 yuan and 8 580.36 yuan,respectively.CONCLUSION: Group MMC is the preferable one among the three groups.
RESUMO
OBJECTIVE: To study the compatibility stability of aztreonam after mixing with fructose injection, calorose injection and xylital injection. METHODS: The content of solution, quantity of particles, pH value and physical changes were observed after aztreonam mixing with 3 kinds of injections for 6 hours at room temperature. RESULTS: The content of solution, quantity of particles, pH value and physical changes were up to the standard. CONCLUSION: Aztreonam mixed with fructose injection, calorose injection or xylital injection is keeping stable.