RESUMO
Studies on pre-clinical toxicity were undertaken to determine the haematological and biochemical changes after administration of alcoholic extract of leaf-stalk of P. betle in rats and mice. Acute and chronic toxicity experiments were performed on mice and rats according to WHO protocol. Different doses of plant extractive were administered for toxicity studies on short and long term basis. Haematological, biochemical profiles and enzymatic studies (transaminases and phosphatases) indicated that the drug (plant extractive) was devoid of toxicity.
Assuntos
Magnoliopsida/química , Animais , Avaliação Pré-Clínica de Medicamentos , Enzimas/metabolismo , Feminino , Rim/efeitos dos fármacos , Fígado/efeitos dos fármacos , Masculino , Camundongos , Tamanho do Órgão/efeitos dos fármacos , Extratos Vegetais/administração & dosagem , Plantas Medicinais/química , RatosRESUMO
Description of a new species of sandfly Phlebotomus sundarai sp. nov. collected from Kala-azar endemic blocks-Gosaba and Baruipur, of district South 24-Parganas, West Bengal is given.
Assuntos
Animais , Doenças Endêmicas , Feminino , Índia/epidemiologia , Leishmaniose Visceral/epidemiologia , Masculino , Phlebotomus/anatomia & histologia , Especificidade da Espécie , Saúde da População UrbanaAssuntos
Animais , Bovinos/parasitologia , Comportamento Alimentar , Interações Hospedeiro-Parasita , Humanos , Índia , Insetos Vetores , PhlebotomusAssuntos
Animais , Ecologia , Feminino , Insetos Vetores , Larva , Leishmaniose Visceral/transmissão , Oviposição , Phlebotomus/parasitologia , Solo/parasitologiaRESUMO
In a model experiment, seed extracts were applied to different bacterial test organisms. Different fractions of seed extracts in petroleum ether (60-80 degrees C) of Lagerstroemia speciosa (Linn. ex. Murray) Pers. when applied to both Gram positive and Gram negative test bacteria, some fractions showed high antagonistic activity.
Assuntos
Antibacterianos/química , Bactérias/efeitos dos fármacos , Éteres , Índia , Extratos Vegetais/farmacologia , Plantas Medicinais/química , Sementes/químicaRESUMO
Extracts from different parts of plants (1) including seeds are reported to act upon pathogenic microorganisms. A few active principles were isolated. The present preliminary report shows significant role of the seeds of Dolichos biflorus (Linn), locally known as Kulthi, against some test organisms using different fractions of defatted seed extracts with methanol.