RESUMO
Background: obesity and overweight are recognized as a growing global health problem Worldwide, prevalence of overweight or obesity, defined as an adult body mass index [BMI] of 25 kg m[2] or greater. Patterns of overweight and obesity differ between countries, regions and by country income, with overweight or obesity more prevalent among men in developed countries and among women in developing countries
Aim of the Work: this study aimed to evaluate the impact of female increased body mass index [BMI] on implantation rate and clinical pregnancy in women undergoing ICSI cycle
Patients and Methods: this is a retrospective study conducted on a total of 400 cycles of assisted reproduction treatment has been evaluated from Orabi IVF Centre and Mit_Ghamr IVF Centre. Data recruited from patient files from January 2016 to July 2018 who did ICSI trial during this period. Patients who included in our study were sub divided into 2 groups according to BMI: 1st group: normal weight with BMI between 18 and 24.9 kg/m2. [200 case], 2nd group: overweight and obese women >/= 25 kg/m2 [200 case]
Results: we showed that overweight and obese infertile women had a higher basal serum FSH, LH and estradiol levels than normal weight women. In our study group the duration of infertility was progressively higher as BMI increased. The two groups were comparable regarding female age were not statistically different in both groups. The duration of infertility showed no significant difference between the two groups. As in group [1] it range from 10-17 years with median duration of 6 years, while in group [2] it range from 0.5-23 with median duration of 5 years this result a significant difference with p value [0.057]
Conclusion: female overweight and obesity appeared to have deleterious effects on ovarian response to stimulation in women undergoing IVF and implantation rate. Moreover, female obesity compromised IVF outcome
RESUMO
Background: One of the basic steps of an infertility workup is to evaluate the shape and regularity of the uterine cavity. Acquired uterine lesions, such as uterine fibroids, endometrial polyps, intrauterine adhesions, or all of these, may cause infertility by interfering with proper embryo implantation and growth
Aim of the Work: to compare the findings of hysterosalpingography, saline infusion transvaginal sonohysterography and Doppler studies in patients with suspected uterine causes of infertility
Patients and Methods: This is a comparative observational cross sectional study, which was conducted in the Obstetrics and Gynecology Department at Al Hussein and Sayed Galal University Hospitals, Al Azhar University in Cairo during the period from April 2017 to the end of September 2018. Sixty patients were included at the study who were recruited from the infertility outpatient clinics, with suspected uterine factors of infertility clinically, by hysterosalpingography [HSG] or by ultrasound
Results: HSG showed the highest sensitivity in the diagnosis of bicornuate uterus, septate uterus and intrauterine synechia [100%] followed by endometrial polyp [70%] then submucous myomas [62.5%]. High specificity [100%] was in the diagnosis of endometrial polyp and submucous myoma. Also it showed high false negative values as it missed the diagnosis of 7 cases
Conclusion: SIS is the gold standard of our study in assessment of uterine factor of infertility. Doppler studies showed high false negative results compared to HSG and saline infusion sonohysterography [SIS]. Some lesions were missed from HSG and diagnosed by SIS and these missed lesions may play a role in infertility, so SIS is very important modality in diagnosis and assessment of uterine factor of infertility
RESUMO
Background: Preeclampsia is a disorder of widespread vascular endothelial malfunction and vasospasm that occurs after 20 weeks' gestation and can present as late as 4-6 weeks post-partum. It is clinically defined by hypertension and proteinuria, with or without pathologic edema
Aim of the Work: is to study the effect of pravastatin given for primigravidae from 13th week to 16th week of gestation on the incidence of preeclampsia compared to a control group in Egyptian women
Subjects and methods: This prospective case control study included 400 pregnant women presenting for routine antenatal care at 13th to 16th weeks' gestation at EL Sayed Galal Obstetric outpatient clinic, Al-Azhar University
Results: In our study, 16 cases developed preeclampsia in the control group [11 cases were severe and the remaining 5 were mild] with a percentage of 8% instead of 6 cases in the study group [4 cases were severe and 2 were mild] with a percentage of 3%
Conclusion: Pravastatin can be used as an effective agent in the prevention of preeclampsia in newborns within neonatal period including fetal weight, gestational age at time of delivery and NICU admission. However, extended follow up is needed till the age of 5 years to assess cognitive functions and school performance among children born for women who received pravastatin for prevention of preeclampsia