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J. biomed. eng ; Sheng wu yi xue gong cheng xue za zhi;(6): 1186-1190, 2013.
Artigo em Chinês | WPRIM | ID: wpr-259743

RESUMO

The conductivity and permittivity of blood in mice were measured by the AC electrical impedance method at frequency range of 0.1-100MHz, and then the changes of the Cole-Cole parameters of dielectric spectra of blood from phenylhydrazine-induced anemia mice were observed by numerical calculation and curve fitting residual analysis of the Cole-Cole equation. The results showed that hematocrit (Hct) of the mice with phenylhydrazine injection was significantly reduced; the permittivity(epsilon) spectroscopy of blood moved to the low insulating region and its permittivity decreased; conductivity (kappa) spectrum curve of blood moved to the high conductivity zone and conductivity increased; the 2nd characteristic frequency was lower than that in the normal group. There was phenylhydrazine dose dependent in the changes of the Cole-Cole parameters of dielectric spectra of blood.


Assuntos
Animais , Camundongos , Anemia , Sangue , Fenômenos Fisiológicos Sanguíneos , Condutividade Elétrica , Impedância Elétrica , Hematócrito
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