RESUMO
Background & objectives: Stature is considered as the height of a person measured in erect position. It is one of the most important factors in establishing identity of a person. In certain medico-legal cases, where only parts or fragments of human body are found. Such a need arises when there is mass casualty. Aim of current study was to establish anthropometric correlation of stature with hand length and foot length in population of Gujarat and also to derive regression equations for correct estimation of stature of male and female in Gujarati population. Material and Method: 150 asymptomatic, apparently healthy, adolescent and adult medical students with age between 18 to 22 years belonging to various regions of Gujarat were selected. Left foot and left hand was selected for measurement. Result: Regression equation for estimation of height using both foot length and hand length were formulated. By using the derived regression equations, height of subjects was calculated and then compared with actual height of subjects. Conclusion: By the present study we conclude that both foot and hand length can be used in estimation of stature of both males and females with fairly accurate results in Gujarati population.
RESUMO
A simple, precise and rapid reverse-phase HPLC method has been developed and subsequently validated for the simultaneous estimation of Amlodipine besylate and Enalapril maleate from their combination drug product. The proposed RP-HPLC method utilizes a Phenomenex C18, 5 μm, 250 mm × 4.6 mm i.d. column, at ambient temperature, optimum mobile phase consisted of Methanol: Acetonitrile : Water (40:50:10, v/v/v), effluent flow rate monitored at 1.0 mL min-1, and detection using PDA detector. The described method was linear over the range of 0.5-6.0 g/ml and 0.5-8.0 g/ml for Enalapril maleate and Amlodipine besylate, respectively. The mean recovery was found to be 100.06 ± 0.49 % and 99.98 ± 0.63 % for Enalapril maleate and Amlodipine besylate, respectively. The intermediate precision data obtained under different experimental setup, the calculated value of coefficient of variation (CV, %) was found to be less than critical value. The proposed method can be useful in the quality control of bulk manufacturing and pharmaceutical dosage forms.
RESUMO
A descriptive study was conducted among tetanus cases admitted to epidemic disease hospital (EDH), Bangalore from October 2006 to March 2007 to describe the socio demographic characteristics of tetanus cases, the clinical presentation and the treatment given to tetanus cases. A total of 80 cases were admitted during this period. Out of the 80 tetanus cases, 71% were from rural area, 55% unimmunized, 47.5% were agricultural workers. A total of 25 (31.25%) deaths were observed during the study period. No case was administered anti tetanus serum outside the epidemic disease hospital.