1.
Indian J Biochem Biophys
;
1989 Apr; 26(2): 109-19
Artigo
em Inglês
| IMSEAR
| ID: sea-27951
RESUMO
The application of McGhee and von Hippel's general equation [J. Mol. Biol., 86 (1974), 469-489, Eq. (15)] to the analysis of the interaction of intercalative drugs with DNA has been further simplified. The value of n can now be determined mathematically, using a simple function, and without any approximation. It is also established that the summation of squared deviation of (( (nu/c), nu)) points would be minimum for and only for the true set of (K,n,omega) of the interaction system. The method incorporating the simplification has been applied to determine the binding parameters of adriamycin-DNA interaction according to the above general equation.
Assuntos
Animais , Bovinos , DNA/efeitos dos fármacos , Interações Medicamentosas , Substâncias Intercalantes/farmacologia , Matemática
2.
Indian J Biochem Biophys
;
1986 Aug; 23(4): 197-203
Artigo
em Inglês
| IMSEAR
| ID: sea-27348
3.
J Indian Med Assoc
;
1954 Oct; 24(1): 1-4
Artigo
em Inglês
| IMSEAR
| ID: sea-101735
4.
J Indian Med Assoc
;
1953 Jul; 22(10): 393-6
Artigo
em Inglês
| IMSEAR
| ID: sea-103186