1.
J Biosci
;
1988 Jun; 13(2): 123-128
Artigo
em Inglês
| IMSEAR
| ID: sea-160649
RESUMO
Lanthanum chloride (1 mM) inhibits the activity of acetylcholinesterase in vitro in the human erythrocyte membrane. Lineweaver-Burk analysis indicates that lanthanum chloride induced inhibition of acetylcholinesterase activity is competitive in nature. The Arrhenius plot shows that the transition temperature of erythrocyte membrane-bound acetylcholinesterase is significantly reduced in the presence of lanthanum chloride. These results suggest that lanthanum chloride increases the fluidity of the erythrocyte membrane and this may be a cause of inhibition of membrane-bound acetylcholinesterase activity.