Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: A distinct clinicopathologic entity

Objective: The objective of this study is to retrospectively evaluate follicular variant of papillary thyroid carcinoma (FVPTC) and reclassify encapsulated FVPTC as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) according to the criteria proposed by The Endocrine Pathology Society working group in 2015 to correlate with outcome. Materials and Methods: Retrospective review of case records of all patients diagnosed as carcinoma of thyroid between 2015 and 2016 was done for the histologic subtype. Gross and microscopic features on resected specimens of FVPTC were reviewed and subtyped as invasive and encapsulated based on capsular/vascular invasion; the encapsulated forms were further studied for size, number, follicular architecture, nuclear features, presence of psammoma bodies, stromal fibrosis, necrosis, mitoses, and lymph node status. Results: Out of the 383 patients with thyroid carcinomas in the study period, 349 were PTC which included 106 FVPTC. Thirty-three patients fulfilled the criteria to be labeled as NIFTP. Total thyroidectomy was performed in 8 patients and hemithyroidectomy in 25 patients. Lymph node dissection along with total thyroidectomy was done in 3 and completion thyroidectomy following hemithyroidectomy was done in 9. There were 29 single and 4 multiple lesions with size varying from 0.2 to 7 cm including 5 lesions measuring <1 cm. The involvement was confined to one lobe in 31 and both lobes in 2 specimens. Patients are on follow-up with no recurrence till date. Conclusion: Thyroid carcinomas currently diagnosed as FVPTC should be evaluated for criteria of NIFTP to avoid overtreatment as they have an indolent behavior.

Prevalence of dental caries and treatment needs among children of Cuttack (Orissa).

An epidemiological investigation was carried out to know the prevalence of Dental Caries amongst 1257 children in the age group of 5, 8, 11 & 15 years respectively attending schools in the city of Cuttack, Orissa. The examination was carried out under natural light and dental caries was diagnosed according to W.H.O. Criteria 1983. The point prevalence of dental caries was recorded to be 64.3% with an average DMFT of 2.38. The prevalence of caries showed a pattern of occurrence i.e. prevalence consistantly increased from 5 years to 8 years age group and subsequently decreased at 11 years and 15 years age. Regarding treatment needs, 63.6% children required dental treatment for various reason and it is in accordance with dental caries prevalence of different age group.