Assuntos
Adulto , Coagulação Sanguínea , Feminino , Fibrose , Humanos , Hipertensão Portal/sangue , Masculino , Veia Porta/patologia , Estudos ProspectivosAssuntos
Adulto , Portador Sadio/imunologia , Ensaio de Imunoadsorção Enzimática , Feminino , Hepatite B/epidemiologia , Antígenos de Superfície da Hepatite B/análise , Vacinas contra Hepatite B/administração & dosagem , Antígenos E da Hepatite B/análise , Humanos , Índia/epidemiologia , Lactente , Recém-Nascido , Masculino , Gravidez , Complicações Infecciosas na Gravidez/epidemiologia , Prevalência , Fatores de Risco , Fatores SexuaisRESUMO
A 30-year old woman presented with recurrent and massive bleeding from gastrointestinal tract. Her coagulation profile revealed von Willebrand's disease and her endoscopic examination showed extensive telangiectasia localized to the gastrointestinal tract. The association of Von Willebrand's Disease and telangiectasia is extremely rare and hence the report.
Assuntos
Adulto , Sistema Digestório/patologia , Endoscopia Gastrointestinal , Evolução Fatal , Feminino , Seguimentos , Hemorragia Gastrointestinal/diagnóstico , Humanos , Telangiectasia Hemorrágica Hereditária/diagnóstico , Doenças de von Willebrand/diagnósticoRESUMO
One hundred term exclusively breast fed babies weighing more than 2.5 kg were evaluated to determine the efficacy of various modes and doses of Vitamin K to prevent hemorrhagic disease of newborn (HDN). The babies were grouped into four categories of 25 each: Group A--1 mg Vitamin K intramuscular (Menadione sodium disulphite) at birth; Group B--0.5 mg Vitamin K intramuscular; Group C--1 mg Vitamin K orally, and group D--no Vitamin K. The prothrombin index was estimated in all babies between 36-72 hours of age. The results revealed a prothrombin index in Groups A, B, C and D as 94.98 +/- 7.64%, 95.08 +/- 9.91%, 92.51 +/- 10.10% and 80.39 +/- 15.90%, respectively. The differences between Groups A, B and C were insignificant. However, Group D, prothrombin index was significantly reduced as compared with the other three groups. It is, therefore, concluded that oral Vitamin K is as effective as injectable Vitamin K and its usage is recommended in our country to reduce complications and costs of parenteral therapy.
Assuntos
Administração Oral , Aleitamento Materno , Feminino , Sangramento por Deficiência de Vitamina K/prevenção & controle , Humanos , Recém-Nascido/sangue , Injeções Intramusculares , Masculino , Estudos Prospectivos , Tempo de Protrombina , Vitamina K/administração & dosagemRESUMO
One hundred and ten bone marrow trephine biopsies were studied from January 1987 to July 1989, using Zenker's acetic acid as fixative and routine paraffin embedding. Trephine biopsies were useful in differential diagnosis of cytopenias, especially when bone marrow aspiration was hypocellular or a dry tap, and in staging of lymphomas and multiple myeloma.
Assuntos
Biópsia por Agulha/instrumentação , Medula Óssea/patologia , Doenças da Medula Óssea/patologia , Diagnóstico Diferencial , Técnicas Histológicas , Humanos , Fixação de TecidosRESUMO
Of forty multi-transfused thalassemia patients (26 males, 14 females; mean age 8.1 +/- 5.3 years, range 1-35) with no clinical or biochemical evidence of liver disease, HBsAg, anti-hepatitis C virus and anti-human immunodeficiency virus antibodies were present in 18 (45%), 7 (17.5%) and 1 (2.5%) cases respectively. Three of the 18 (16.7%) HBsAg positive patients were anti-delta antibody positive. Our results indicate that more than 50% of multi-transfused thalassemia patients show serological evidence of one or more of hepatitis B, C and D and human immunodeficiency virus infection.