Morbidity and mortality of acute myocardial infarction in and around Aligarh.

A 6-year retrospective study of 341 cases of acute myocardial infarction admitted to JN Medical College Hospital, Aligarh in respect of the incidence, complications and mortality in relation to age, sex, religion, smoking habit occupation and risk factors was made. The incidence was found to be 9 per 1000 hospital admissions. Maximum number of cases was in the age group of 51-60 years and male to female ratio was 7:1. There was no significant difference in incidence and mortality between Hindus and Muslims of both sexes. Highest incidence was noted among sedentary workers and smokers. Hypercholesterolaemia was found in only 17.01% cases, the rest having normal serum cholesterol levels. Hypertension and diabetes mellitus were associated in 24.05% and 12.32% cases respectively. Cardiac complications were noted in 43.4% of patients, the commonest being cardiac failure. Overall in-hospital mortality was observed to be 11.41% of which 79.49% had cardiac complications. Diabetics had significantly (p less than 0.05) higher mortality rate (21.43%) as compared to non-diabetics. Smokers had higher mortality rate compared to non-smokers (p less than 0.01). Although those with hypertension and with hypercholesterolaemia had higher mortality, the results were not statistically significant. The average day of expiry after acute myocardial infarction was 3.82 days during hospital stay.

Serum and tissue sodium/potassium changes in estrogen treated female albino rats.

Five control and ten estrogen treated albino rats were studied for changes in sodium and potassium in serum, heart, muscle, uterus and brain. The serum levels of sodium depleted significantly in the estrogen treated rats. Of the tissues studied, only uterus and brain had significantly sodium retention effect. The potassium levels on the other hand decreased significantly, both in serum and tissues following treatment with estrogen.