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1.
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 1212-1215, 2014.
Artigo em Chinês | WPRIM | ID: wpr-313050

RESUMO

<p><b>OBJECTIVE</b>To explore different regulatory effects of electroacupuncture (EA) at the same acupoint on the heart and the stomach.</p><p><b>METHODS</b>Eighty male SD rats were randomly divided into eight groups equally, i.e., the Neiguan (PC6) group, the Quchi (LI11) group, the Tianshu (ST25) group, the Danzhong (RN17) group, the Zusanli (ST36) group, the Sanyinjiao (SP6) group, the Xinshu (BL15) group, and the Weishu (BL21) group, 10 in each group. The regulatory effects of EA (2/15 Hz, 3 mA, 2 min) at different acupoints on the gastric motility (intragastric pressure) and the cardiac function (the left ventricular pressure) were observed. The mean values of effect of two-min pre-EA and after-EA were compared.</p><p><b>RESULTS</b>Compared with the pre-EA in the same group, the left ventricular pressure decreased in the Neiguan (PC6) group, the Quchi (LI11) group, the Danzhong (RN17) group, the Sanyinjiao (SP6) group, and the Xinshu (BL15) group (P <0.05). The intragastric pressure increased in the Quchi (LI11) group, the Zusanli (ST36) group, the Sanyinjiao (SP6) group, and the Xinshu (BL15) group, while it decreased in the Tianshu (ST25) group, the Danzhong (RN17) group, and the Weishu (BL21) group (P <0.05). The difference of the left ventricular pressure was sequenced from high to low as Xinshu (BL15) >Danzhong (RN17) >Neiguan (PC6) >Sanyinjiao (SP6) >Quchi (LI11). The difference of the intragastric pressure was sequenced from high to low as Tianshu (ST25) >Weishu (BL21) > Xinshu (BL15) > Danzhong (RN17) > Zusanli (ST36) > Sanyinjiao (SP6) > Quchi (LI11).</p><p><b>CONCLUSIONS</b>EA at the same acupoint (2/15 Hz, 3 mA) showed different regulatory effects on the heart and stomach. There existed some difference in the direction and size due to the acupoint location, meridians, dominant nerve segment or relating organs. A fixed effect direction to the specific target was also shown.</p>


Assuntos
Animais , Masculino , Pontos de Acupuntura , Eletroacupuntura , Coração , Fisiologia , Meridianos , Ratos Wistar , Estômago , Fisiologia
2.
Chinese Acupuncture & Moxibustion ; (12): 765-768, 2012.
Artigo em Chinês | WPRIM | ID: wpr-280805

RESUMO

Relative literatures on the two-way regulatory eltect ot acupuncture on gastrointestInal muiiiity 01 inc recent 20 years were retrieVed in CNKI. Researches on effects of acupuncture on electrical activity of the gastric muscle, and mechanism of nerve and humor were summarized. And the result shows that the two-way regulatory effect of acupuncture on gastrointestinal motility function which eventually causes the recovery of gastrointestinal function, is a benign regulation reached by relative antagonism and inter-coordination of the neural, endocrine and immunity in all aspects. Meanwhile, the detailed conditions of the experiments are not strictly controlled, the intervention methods are not unanimous, the indices of observation are not unified, and the results are lack of scientificalness, regularity and corporeality. It is proposed that the future research should be carried out in the following 3 aspects, namely whether single points have the two-way regulatory effect or not; the application of single points in point prescriptions and the variety of quantity; and differences on the two-way regulatory effect and working processes between acupuncture and medication.


Assuntos
Animais , Humanos , Terapia por Acupuntura , Gastroenteropatias , Terapêutica , Motilidade Gastrointestinal , Trato Gastrointestinal
3.
Chinese Acupuncture & Moxibustion ; (12): 871-876, 2012.
Artigo em Chinês | WPRIM | ID: wpr-246357

RESUMO

<p><b>OBJECTIVE</b>To observe the efficacy of acupuncture and moxibustion on female obesity complicated with climacteric syndrome and its impact factors.</p><p><b>METHODS</b>One hundred and fifty-one cases of female obesity complicated with climacteric syndrome were treated according to the basic principle as "pattern/syndrome differentiation". Accordingly, the reinforcing or reducing technique was applied at Quchi (LI 11), Zhongwan (CV 12), Tianshu (ST 25), Daheng (SP 15), Zusanli (ST 36), Shangjuxu (ST 37), Sanyinjiao (SP 6), Neiting (ST 44), etc. The auricular point sticking was applied at Hunger Point, Ear-shenmen, Sympathetic Nerve, Endocrine and Stomach. The treatment was given once every two days. The duration of treatment was 3 months. The changes in the symptoms, physical signs, obesity index, Kupperman index, the vegetative equilibrium index (Value Y), estradiol (E2) and follicle stimulating hormone (FSH) were observed before and after treatment.</p><p><b>RESULTS</b>The obesity patients complicated with climacteric syndrome presented unusually high level of obesity index, Kupperman index and FSH levels and unusually low level of E2. After treatment, the obesity index, Kupperman index and FSH levels were all reduced significantly (all P < 0.01) while E2 level was increased significantly (P < 0.05).</p><p><b>CONCLUSION</b>Acupuncture and moxibustion achieve the significant efficacy on obesity complicated with climacteric syndrome, which is closely related with the pattern/syndrome of the disorder and obesity grade. For the effective and curative rate of obesity index, the efficacy of liver qi stagnation pattern/syndrome is better than that at liver stagnation and spleen deficiency pattern/syndrome than spleen and kidney yang deficiency pattern/syndrome than liver and kidney yin deficiency pattern/syndrome than yin and yang deficiency pattern/syndrome; the efficacy of mild obesity is better than that at moderate obesity than severe obesity.</p>


Assuntos
Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Terapia por Acupuntura , Moxibustão , Obesidade , Metabolismo , Terapêutica , Pós-Menopausa , Metabolismo
4.
China Journal of Chinese Materia Medica ; (24): 1429-1432, 2007.
Artigo em Chinês | WPRIM | ID: wpr-287941

RESUMO

<p><b>OBJECTIVE</b>To investigate the ulcer-preventive effect of bismuth glycyrrhizate on experimental gastric ulcer and its mechanisms.</p><p><b>METHOD</b>Three kinds of model animals with experimental gastric ulcer were established and gastric mucosal injuries were induced by pyloric ligation in rats, applying ethanol in rats and imposing stress in mice, respectively. The rats were divided into experimental groups treated with bismuth glycyrrhizat 700, 350, 175 mg kg(-1), positive control group treated with cimetidine (200 mg kg(-1), and negative control group treated with 0.1% EDTA. The mice were divided into experimental groups treated with bismuth glycyrrhiza 980, 490, 250 mg kg(-1). The gastric ulcer index, gastric juice volume, acidity, pepsin activity, the level of nitric oxide (NO) in serum and the level of prostaglandin E2 in gastric tissue were measured in rats.</p><p><b>RESULT</b>Bismuth glycyrrhizate was shown to be able to reduce the gastric juice volume, acidity and pepsin activity as well as gastric ulcer index. It could increase the content of NO in serum and the content of prostaglandin E2 in gastric tissue.</p><p><b>CONCLUSION</b>The bismuth glycyrrhizate has antiulcer effect in rats.</p>


Assuntos
Animais , Feminino , Masculino , Camundongos , Ratos , Antiulcerosos , Farmacologia , Bismuto , Farmacologia , Dinoprostona , Metabolismo , Mucosa Gástrica , Metabolismo , Patologia , Ácido Glicirrízico , Farmacologia , Óxido Nítrico , Sangue , Pepsina A , Metabolismo , Fitoterapia , Ratos Sprague-Dawley , Úlcera Gástrica , Metabolismo , Patologia
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