RESUMO
Background: Old age is often accompanied by frailty and diseases including neuropsychiatric disorders. De-mentia and depression are the most common neuropsychiatric disorders among the elderly. Kerala has the maximum proportion of elderly in its population and successful identification of the elderly at risk is im-portant for early intervention. The purpose of the study is to estimate the prevalence of depression and asso-ciated factors among the elderly population. Methods: A cross-sectional study was conducted among 320 elderlies from July 2018 to July 2019.The preva-lence of depression was estimated using GDS-15. Socio-demographic factors, self- perceived health status, morbidity profile, falls and related factors, religious practices, independence in activities of daily living, and other social factors associated with depression were assessed. Results: 38.1% of the elderly were depressed. Majority had mild depression (23.4%) and 3.1% were severely depressed. Having no formal education, low socioeconomic status, not living with a spouse, no role in decision -making, average or poor self-perceived health status, past surgical history, and fear of falls were found to be independent predictors of depression. Conclusion: The prevalence of depression was high among elderly. Screening for depression in the elderly should be incorporated in already available programs along with appropriate health care measures.
RESUMO
Background: The aim of the study was to evaluate average age of menarche, the pattern and types of menstrual disorders and their relation with BMI, dietary habits, physical exercise and stress.Methods: A cross sectional prospective study was conducted on female medical students during the academic year 2018-2019 at Mallareddy medical college for women, Suraram, Hyderabad, India. The various life style factors including BMI, junk food consumption and physical exercise were factored. Prevalence of each different menstrual abnormality were identified and analyzed by Chi-squire test and p value <0.005 was considered as statistically significant.Results: Study included 255 medical students who had attained menarche without known medical problems. Mean age of menarche was 12.81years. The most frequent menstrual disorders were premenstrual syndrome 192 (75 %), dysmenorrhoea 146 (57 %), and irregular cycle 97(38%). Statistically significant association of Body mass index (BMI) related to premenstrual syndrome (PMS) and dysmenorrhoea was reported (both p<0.05). Similarly, statistically significant association of lack of physical activity had greater risk of premenstrual syndrome and dysmenorrhoea (both p<0.0001). Unhealthy dietary patterns had statistically significant higher risk for dysmenorrhoea (p<0.0001).Conclusions: In conclusion premenstrual symptoms, dysmenorrhoea and menstrual irregularities were more prevalent. Majority of symptoms were stress, pain abdomen, irritability, mood swings. Comprehensive education programs on lifestyle modifications like regular physical activities, promoting healthy eating habits should be emphasised to prevent menstrual abnormalities of young students as early as at school level.
RESUMO
The present research work was aimed to develop matrix tablets of Glimepiride with Aloe barbadensis miller leaves mucilage and Povidone and to study its functionality as a matrix forming agent for sustained release tablet formulations. Physicochemical properties of dried powdered mucilage of Aloe barbadensis miller mucilage and Povidone tablet blend were studied. Various formulations of Glimepiride Aloe barbadensis miller mucilage and Povidone were prepared. They found to have better satisfactory physicochemical properties with low SD values. The swelling behavior and release rate characteristics were studied. The dissolution study proved that the dried Aloe barbadensis miller mucilage and Povidone combination can be used as a matrix forming material for making Sustained release matrix tablets.
RESUMO
Among 150 patients with dermatophytosis studied, tinea corporis was the commonest clinical type, followed by tines cruris. The overall positivity by culture was 45.3% and by direct microscopy 64%. T. rubrum was the commonest species isolated (66.2%) followed by TI mentagrophytes (25%).