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Objective To assess the estimated 10-year risk of stroke among hypertensive outpatients known with diabetes from cardiovascular clinics of 36 tertiary hospitals in China and to analyze the characteristics of the risk factors and the 10-year risk of stroke between the southern and the northern patients.Methods A multi-center prevalence survey was conducted from October 2011 to June 2012.Hypertensive outpatients known with diabetes were enrolled from cardiovascular clinics of 36 tertiary hospitals in China.A total of 15 914 outpatients were included in the final analysis.The 10-year probability of stroke was evaluated by the Framingham stroke risk profile.According to the 10-year probability of stroke,patients were divided into low risk (≤ 5％),medium risk (6％ ～9％) and high risk (≥10％).Results (1) Of all the hypertensive outpatients known with diabetes,the mean age was (64.6 ± 10.1) years and the mean systolic pressure was (138.7 ± 19.3) mmHg(1 mmHg =0.133 kPa).Among them,7.4％ with atrial fibrillation,11.2％ with left ventricular hypertrophy,57.2％ with cardiovascular diseases,17.1％ smokers and 37.0％ using mono-hypoglycemic agent.The southern patients who were older with more smokers had higher proportions of men and left ventricular hypertrophy,lower Levels of systolic blood pressure,and lower proportions of other cardiovascular diseases than those of the northern patients (all P ＜ 0.05).(2) The mean 10-year probability of stroke was (20.9 ± 16.2) ％.The southern patients had a higher mean 10-year probability of stroke than that of the northern patients [(22.4 ± 17.1)％ vs (19.7 ± 15.2)％] (P ＜ 0.01).After adjusted by age and sex,the southern patients still had a higher mean 10-year probability of stroke (P ＜0.05).(3) All the patients had 7.7％ with low risk,17.4％ with medium risk,and 74.9％ with high risk.The southern patients had lower proportions of low and medium risk than those of the northern patients (6.7％ vs 8.4％,15.5％ vs 18.9％),but had a higher proportion of high risk than that of the northern patients (77.7％ vs 72.7％,all P ＜ 0.01).Conclusions Among the hypertensive outpatients known with diabetes from the cardiovascular clinics of our study,most of them were at the 10-year high risk of stroke.The southern patients had a higher mean 10-year probability of stroke than that of the northern patients.
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Objective:To investigate the prevalence and the related diseases of type 2 diabetes mellitus and impaired glucose tolerance among the old population in Chongqing region.Methods:A cross-section suvery with multiple-stage and random sampling was performed among 1791 elder people over 60 years in Chongqing region.Results:(1)The prevalence of type 2 diabetes mellitus and impaired glucose tolerance were 15.6% and 20.5%,respectively.Postprandial plasma glucose was a sensitive diagnostic standard for type 2 diabetes mellitus of the elder population.(2)The prevalence of type 2 diabetes mellitus and impaired glucose tolerance were significantly different between the over-70-years-old group and the 60～69-years-old group,especially the prevalence of impaired glucose tolerance.(3)Logistic regression analysis showed that hypertension,hypertriglyceridemia,obesity and centric obesity were the risk factors for the prevalence of type 2 diabetes mellitus and impaired glucose tolerance.Conclusion:The prevalence of type 2 diabetes mellitus and impaired glucose tolerance grow with aging,and the postprandial plasma glucose is a sensitive diagnostic standard for type 2 diabetes mellitus of the elder population.Hypertension,hypertriglyceridemia,obesity and centric obesity are the main diseases leading to the prevalence of type 2 diabetes mellitus of the elder population.
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Objective:To investigate the factors related to insulin resistance and islet ? cell secretory function in subjects with normal glucose tolerance(NGT).Methods:Insulin resistance and islet ? cell secretory function were estimated by Homeostasis Model Assessment in 2120 NGT subjects.Results:(1)ANOVA showed that there were significant differences in Homa-IR and Homa-? cell among different age groups(P