RESUMO
AIM: To establish the quality standard of Gusongbao Dispersible Tablets(Herba Epimedii,Radix Dipsaci,Radix Pasoniae rubra,Rhizoma Chuanxiong,etc.) METHODS: Herba Epimedii,Radix Paeoniae rubra,Rhizoma Chuanxiong,Rhizoma Anemarrhenae were identified by TLC.Icariine content was determined by HPLC.C_18 column(ODS,4.6 mm?200 mm,5 ?m) as chromatographic column,acetonitrile-water(30∶70) as mobile phase,flow rate kept to 1.0 mL/min,detection wavelength at 270 nm,and under room temperature condition.The dissolubility test met with Chinese Pharmacopoeia for Icariine. RESULTS: The relevant spots in Herba Epimedii,Radix Paeoniae rubra,Rhizoma Chuanxiong,Rhizoma Anemarrhenae could be identified by TLC.The content of icariine can be determined by HPLC.The linearity of icariine was good in the range of 0.13-0.78 ?g(r=0.999 9).The average recovery of icariine was 98.90%,RSD=0.92%(n=6).Dissolubility test used for icariine coformed to homogeniety. CONCLUSION: The established quality standard is simple,feasible and repeatable,and can be used for quality control of Gusongbao Dispersible Tablets.