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Int. braz. j. urol ; 36(2): 159-170, Mar.-Apr. 2010. graf, tab
Artigo em Inglês | LILACS | ID: lil-548375

RESUMO

PURPOSE: Evaluation of the beneficial effect of nephrectomy of the atrophic kidney on blood pressure (BP) and renal function. MATERIALS AND METHODS: A retrospective study of 51 patients with renovascular hypertension (RVH), bearers of atrophic kidney due to severe stenosis or occlusion of the renal artery. Average age was 47.1 ± 15 years, the median creatinine clearance was 54 mL/min, average systolic BP (SBP) 149.6 ± 22.5 mm Hg, average diastolic BP (DBP) 90.8 ± 17 mm Hg and the median number of hypotensors 3 (1 to 5) per patient per day. Blood pressure and serum creatinine were analyzed from 12 to 60 months after the nephrectomy. RESULTS: There was a significant improvement in the average SBP in the periods from 12 to 36 months (p ≤ 0.028) and for the average DBP from 12 to 48 months after the nephrectomy (p ≤ 0.045), accompanied by a significant reduction in the use of hypotensors from 12 to 48 months (p < 0.05). One year after the nephrectomy, there was a 69 percent improvement in blood pressure and 63.8 percent improvement in renal function of patients. CONCLUSION: The removal of atrophic kidney in patients with RVH is a safe procedure which presents benefits for the control of arterial hypertension and renal function in bearers of renovascular hypertension.


Assuntos
Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Hipertensão Renovascular/cirurgia , Rim/patologia , Nefrectomia/métodos , Artéria Renal/cirurgia , Atrofia/cirurgia , Pressão Sanguínea/fisiologia , Seguimentos , Hipertensão Renovascular/fisiopatologia , Rim/irrigação sanguínea , Rim/cirurgia , Período Pós-Operatório , Período Pré-Operatório , Estudos Retrospectivos , Resultado do Tratamento
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