RESUMO
Background and Objective: Tapak Liman leaves have been long used traditionally for anemia. The dried powder form ofElephantropus scaber was extracted to produce ethanol. This study aimed to prove the hematopoietic effect of tapak limanleaf. Materials and Methods: The study was conducted for 28 days. The samples consisted of one non-anemic group andfour anemic groups induced by 130 mg/kgBW chloramphenicol given every day for 14 days. In the last day, group 2, 3 and 4were given the extract of tapak liman leaves for 10, 30 and 100 mg/kgBW; respectively. Group 5 (as a positive control) wasgiven physiological NaCl 0.9%. The testing doses were given once a day for 14 days, and the effects were observed on day1st , 14th, 21st, and 28th. Results: The parameters used in this study were erythrocyte, hemoglobin, reticulocyte andhematocrit counts in white mice that were analyzed by two-way ANOVA showing a significant value of (p<0.05).Conclusions: The extract of tapak liman leaves could increase hematopoietic activities; hence, it could be used as analternative therapy for anemia.