RESUMO
Lemierre's syndrome is characterized by anaerobic bacterial infection in the head and neck, causing thrombophlebitis of the jugular vein. This disease is usually associated with a history of pharyngitis. The most common pathogens are Fusobacterium species, particularly Fusobacterium necrophorum. Lemierre's syndrome is seen most commonly in teenagers and young adults. We present a case report of a 67-year-old man with an atypical clinical manifestation of an uncommon pathogen in Lemierre's syndrome with epilepsia partialis continua.
Assuntos
Adolescente , Idoso , Humanos , Adulto Jovem , Infecções Bacterianas , Epilepsia Parcial Contínua , Fusobacterium , Fusobacterium necrophorum , Cabeça , Veias Jugulares , Síndrome de Lemierre , Pescoço , Faringite , Tromboflebite , Trombose VenosaRESUMO
Peripheral neuropathies occur in lymphoma patients. Causes of neuropathy include chemotherapy, opportunistic infections, and the lymphoma itself. We report a patient with lymphoma whose chief complaint was a sensory loss in the hands and feet. Electrophysiologic studies and sural nerve biopsy showed sensory polyneuropathies. We hypothesize that this neuropathy is associated with lymphoma-related ganglionopathy, and among the possible causes, we suspect that a systemic cause such as a paraneoplastic syndrome is the most likely pathogenic etiology. However, further follow-up will be necessary to see whether sensory symptoms change with lymphoma treatment.
Assuntos
Adulto , Humanos , Masculino , Biópsia , Eletrofisiologia , Doença de Hodgkin/complicações , Metástase Linfática , Linfoma/metabolismo , Doenças do Sistema Nervoso Periférico/complicações , Transtornos de Sensação/complicaçõesRESUMO
Charcot-Marie-Tooth disease (CMTD) is a hereditary neuropathy with slow progression, whereas Guillain-Barre syndrome is an acute acquired neuropathy of immunopathogenesis. A 17 year-old girl with hammertoes and pes cavus developed an acute quadriparesis. The duplication of PMP-22 exons in 17p12-p11.2 was confirmed by genetic study. After Intravenous ingection of immunoglobulin, she recovered to normal activity within one month with improvement of nerve conduction study. We should be concerned with the possibility of Guillain-Barre syndrome if there is rapidly progressive exacerbation on CMTD.
Assuntos
Adolescente , Feminino , Humanos , Doença de Charcot-Marie-Tooth , Éxons , Deformidades do Pé , Síndrome de Guillain-Barré , Imunoglobulinas , Condução Nervosa , QuadriplegiaRESUMO
We described 2 patients with Marchiafava-Bignami disease, a neurological disorder associated with chronic alcohol consumption. Patient 1 expressed general weakness and confusion, while patient 2 expressed dysphagia and seizures. Lesions involving the corpus callosum were identified with T2 weighted MR imaging in which there was a hyperintensity in the splenium of patient 1 and in the entire corpus callosum of patient 2. While the conditions of both patients were improved by with nutritional support, they were left with cognitive impairment.