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1.
Journal of the Korean Academy of Family Medicine ; : 774-781, 2007.
Artigo em Coreano | WPRIM | ID: wpr-80939

RESUMO

BACKGROUND: Tsutsugamushi disease, which is caused by Orientia tsutsugamushi, is an acute febrile illness transmitted by infected mites. Recently, the incidence rate has been increased especially in the Daejeon and Chungcheongnam-do. We analyzed the patients with tsutsugamushi disease, who lived in Daejeon and Chungcheongnam-do, to find out their clinical manifestations and factors affecting the disease duration. METHODS: A total of 102 patients who were diagnosed with tsutsugamushi disease at the department of family medicine in a university hospital from September 2005 to November 2005 were studied. We analyzed their clinical characteristics and investigated the clinical factors associated with disease duration in tsutsugamushi disease by multiple regression analysis. The term "disease duration" was defined as the interval from symptom onset to discharge. RESULTS: Among 102 patients, 33 were males and 69 were female, and the mean age was 57.4 years. The average interval from symptom onset to admission was 6.6 days. The average interval from symptom onset to discharge was 14.5 days. From multiple regression analysis, interval from symptom onset to admission (beta=0.470, P<0.001), serum albumin level (beta=-3.441, P= 0.019), and abnormal findings of chest X-ray (beta=2.925, P=0.021) were shown to independently contribute to disease duration (R(2)= 0.458). CONCLUSION: Disease duration is significantly correlated with clinical factors such as abnormal findings of the chest X-ray, lower serum albumin level, and longer interval from symptom onset to admission. These factors could be used as parameters of the severity of disease in patients with tsutsugamushi disease.


Assuntos
Feminino , Humanos , Masculino , Incidência , Ácaros , Orientia tsutsugamushi , Tifo por Ácaros , Albumina Sérica , Tórax
2.
Journal of the Korean Academy of Family Medicine ; : 523-531, 2007.
Artigo em Coreano | WPRIM | ID: wpr-37967

RESUMO

Background: Bioelectrical impedance analysis (BIA) is frequently used to diagnose obesity in clinical setting, but the usefulness of BIA in children is not become known accurately. We analyzed the usefulness of BIA and anthropometric measurement compared with Dual-energy X-ray absorptiometry (DXA) as a diagnostic tool of childhood obesity. Methods: 205 volunteer primary and middle school children were recruited. We measured weight and height, and analyzed the body composition by BIA and DXA. By paired t-test and Bland-Altman plots, mean difference and limit of agreement were calculated between DXA and BIA according to sex and age groups. Sensitivity and specificity were displayed with the gold standard of PBF above 35% by DXA. Results: There was significantly positive correlation between DXA and BIA in fat mass (FM) (r=0.982, P<0.001), fat free mass (FFM) (r=0.990, P<0.001), and percent body fat (PBF) (r=0.956, P<0.001). Mean difference between DXA and BIA in FM, FFM, and PBF were -0.4+/-1.4 kg (P<0.001), -0.6+/-1.3 kg (P<0.001), and 0.5+/-2.8% (P=0.016), respectively. Limit of agreement in FM, FFM, and PBF were -0.4+/-2.7 kg, -0.6+/-2.5 kg, and 0.5+/-5.5%, respectively. The most sensitive method of diagnosis of obesity was Korean BMI standards for 85 percentile (94.7%) and IOTF BMI 25 kg/m2 (94.7%). The sensitivity and specificity by BIA were 90.7% and 97.7%. Conclusions: BIA was not interchangeable with DXA. However because of higher diagnostic accuracy and correlation, it could be used to measure body composition as simple field method. We recommend Korean BMI standards for 85 percentile or IOTF BMI 25 kg/m2 as the screening test for diagnosis of Korean childhood obesity.


Assuntos
Criança , Humanos , Absorciometria de Fóton , Tecido Adiposo , Composição Corporal , Diagnóstico , Impedância Elétrica , Programas de Rastreamento , Obesidade , Obesidade Infantil , Sensibilidade e Especificidade , Voluntários
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