Importance of Oral Environment for Environmental Hormones Interaction with Human Body for Future Research

There is increasing evidence that the environmental hormones may adversely affect the human body. The human reproductive system misrecognizes some of these endocrine disruptors with consequences to reproductive cell differentiation. Therefore, studies on the safety of these substances have been widely carried out to develop the science to create effective legislation to limit or prevent their use or require the development of inert, alternative substances. A few studies have reported that the oral cavity is the pathway for absorption of these substances released from plastic products or environmental hormone substances. This review suggests that the oral environment is vulnerable to exposure to environmental hormones and introduces supporting literature.

Hyperintensity of Subarachnoid Space on FLAIR Images Caused by Supplemental Oxygen

A hyperintensity in the subarachnoid space on fluid-attenuated inversion-recovery (FLAIR) images is often caused by diseases such as subarachnoid hemorrhage or meningitis. Oxygen has a known paramagnetic effect and also causes signal changes in the subarachnoid space on FLAIR images. These changes usually develop when the inspired air contains a high oxygen fraction. Here we present a patient with a hyperintensity in the subarachnoid space on FLAIR images whose inspired air contained only a low oxygen fraction.

A Case of Numb-Chin Syndrome Assoicated with Hodgkin's Disease

The numb chin syndrome (NCS) is characterized by chin or lower lip numbness restricted to the distribution of the mental nerve (the distal trigeminal nerve). The authors report a patient whose initial symptom of tumor recurrence was unilateral numbness of the chin. A 65-year-old male was admitted because of paresthesia around the left chin and left lower lip. Neurologic examination revealed hypesthesia on the left side of chin, lower lip and buccal mucous mem-brane. Bone scan (Tc-99m MDP) showed focal hot uptakes on the left mandible and left first rib. Brain CT with bone window setting showed a focal osteolytic lesion in the bone marrow of the left mandibular canal without destruction of bone cortex. Both coronal T1 weighted image and axial T2 weighted image showed focal low signal intensities on the left ramus. The pathophysiologic mechanism could be understood by identification of the pathologic focus.