RESUMO
Introduction: In present study, we examined the effects of endurance training alone and endurance training combined with taking garlic supplement on serum homocysteine levels, complex plasminogen activator [TPA], and body composition parameters such as weight, BMI and body fat percentage in sedentary women
Materials and Methods: Twenty-seven women who used to Alzahra sport clubs of 3 and 4 municipality of Tehran participated in this study [age, 38.53 +/- 7.59 years; weight, 77.61 +/- 5.26 kg]. The subjects were randomly divided into three groups, endurance training, endurance training combined with garlic supplement and the control groups. The training protocol included: Running on a treadmill for 60 minutes at 60 to 75% of maximum heart rate for 10 weeks 5 times a week. Subjects of the training combined with garlic supplement group, received 2 tablets daily [in the form of capsules, 500 mg, nature made]. At the beginning and 48 hours after training, the subjects were assessed for homocysteine and TPA. Data were analyzed using paired t-test and one way ANOVA [P<0.05]
Results: Findings showed that in the endurance training and the endurance training combined with garlic supplement groups, serum homocysteine levels were significantly decreased [p<0.05]. Although, other variables were reduced, but these changes were not statistically significant
Conclusion: According to this study, 10 weeks of endurance exercise with reduction of homocysteine levels, could lead to reduction in the risk of cardiovascular disease in sedentary obese women