Listerial meningoencephalitis: AIDS and non AIDS patients

A total of 11 patients with listeriosis wereadmited to the Hospital Emilio Ribas - Säo Paulo, Brasil. The etiology Listeria monocytogenes in 2 Aids and Listeria spp in underlying conditions was established in the other patients. The age ranged from 20 to 60 years old and white: black; male:famele ratio was 3:1 for all them. Acute meningoencephalitis in 11; renal failure in 2; acute respiratory failure, septicemia and AIDS with drug multiform exantema, respectively in 1 were observed. Leukocytosis > 500 cells/mm elevado ao cubo; glucose < 45 mg/dl; protein > 90 mg/dl and Gram-positive rod strains with positive culture to Listeria spp were revealed in the cerebrospinal fluid study. These strains were resistant to betalactamin; colistin; streptomycin and amikacin and sensitive to kanamicin; gentamicin; tetracicline; erytromicin and chloramphenicol. Monotherapy (ampicillin) or associate (ampicillin/chloramphenicol) had not influence on death or improvement during the follow-up of patients. Listeral meningoencephalitis is similar to tuberculosis or other bacterial meningitis include in cerebrospinal fluid chemistries data

Candidíase em pacientes aidéticos / Candidiasis in AIDS patients

Trinta e cinco aidéticos entre 19 e 55 anos admitidos e tratados de candidíase no Hospital Emílio Ribas, SP, com ELISA positivo para HIV e confirmado pelo Western Blot. Tuberculose em 9 sendo 2 com pericardite; neurotoxoplasmose em 6; neurocriptococose em 5; herpes labial em 4; pneumocistose em 3 e sarcoma de kaposi em 2, achavam-se associadas. A concentraçäo inibitória mínima 50 por cento (MIC 50 por cento) para os azoles foi: ketoconazol = 2,2 µg/ml; itraconazol = 21,0 µg/ml; fluconazol = 19,0 ég/ml. O MIC 50 por cento para os polienos: nistatina = 50,0 µg/ml; anfotericina B = 0,12 µg/ml e para 5 fluorcitosina = 1,6 µg/ml nas 35 amostras de Candida isoladas. Testes näo paramétricos de Siegel revelaram significante identificaçäo (80 por cento) das Candida albicans na candidíase, e que a dose de AMB näo modificou o número de óbitos, precoce e tardio, ocorridos nesses aidéticos. O uso prévio de azoles e da nistatina explicaria, talves, o elevado MIC 50 por cento observado nas amostras de Candida isoladas